D
Diego Eidy Chiba
Researcher at Sao Paulo State University
Publications - 7
Citations - 359
Diego Eidy Chiba is an academic researcher from Sao Paulo State University. The author has contributed to research in topics: Cancer epigenetics & Histone deacetylase 5. The author has an hindex of 4, co-authored 7 publications receiving 263 citations.
Papers
More filters
Journal ArticleDOI
The Prodrug Approach: A Successful Tool for Improving Drug Solubility
Daniela Hartmann Jornada,Guilherme Felipe dos Santos Fernandes,Diego Eidy Chiba,Thais Regina Ferreira de Melo,Jean Leandro dos Santos,Man Chin Chung +5 more
TL;DR: This review aims to describe recent advances in the improvement of solubility via the prodrug approach, highlighting the advances of this field in the last ten years.
Journal ArticleDOI
Unraveling the Anticancer Effect of Curcumin and Resveratrol.
Aline Renata Pavan,Gabriel Dalio Bernardes da Silva,Daniela Hartmann Jornada,Diego Eidy Chiba,Guilherme Felipe dos Santos Fernandes,Chung Man Chin,Jean Leandro dos Santos +6 more
TL;DR: This work analyzed the anticancer activity of resveratrol and curcumin reported in the literature in the last 11 years in order to unravel the molecular mechanism of action of both compounds.
Journal ArticleDOI
Epigenetic Regulatory Mechanisms Induced by Resveratrol.
Guilherme Felipe dos Santos Fernandes,Gabriel Dalio Bernardes da Silva,Aline Renata Pavan,Diego Eidy Chiba,Chung Man Chin,Jean Leandro dos Santos +5 more
TL;DR: The biological activities exhibited by RVT are analyzed with a focus on the epigenetic mechanisms, especially those related to DNA methyltransferase, histone deacetylase and lysine-specific demethylase-1 (LSD1).
Journal ArticleDOI
Antiplatelet activity and TNF-α release inhibition of phthalimide derivatives useful to treat sickle cell anemia
Rafael Consolin Chelucci,Isabela Junqueira Oliveira,Karina Pereira Barbieri,Maria Elisa Lopes-Pires,Marisa Campos Polesi,Diego Eidy Chiba,Iracilda Zeppone Carlos,Sisi Marcondes,Jean Leandro dos Santos,ManChin Chung +9 more
TL;DR: In this paper, the antiplatelet activity and the ability to reduce tumor necrosis factor-α (TNF-α) levels of phthalimide derivatives were described.
Journal ArticleDOI
HIV latency reversal agents: A potential path for functional cure?
TL;DR: In this article, the authors focus on the promising LRAs that have been described in the literature over the past few years, highlighting the advantages and disadvantages of their use in the 'kick and kill' approach, thus opening a new avenue in the development of a potential cure.