D
Dinesh M. Dhumal
Researcher at Aix-Marseille University
Publications - 21
Citations - 205
Dinesh M. Dhumal is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Dendrimer & Chemistry. The author has an hindex of 7, co-authored 17 publications receiving 124 citations. Previous affiliations of Dinesh M. Dhumal include Institute of Chemical Technology.
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Self-microemulsifying drug delivery system of curcumin with enhanced solubility and bioavailability using a new semi-synthetic bicephalous heterolipid: in vitro and in vivo evaluation
TL;DR: The heterolipid, E1E, proved to be an efficient solubility and bioavailability enhancer for curcumin for formulation development of its SMEDDS, and suggested potent anticancer, antibacterial activity and non-cytotoxicity of developed Curcumin-E1E_SMEDDS5e.
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Development and validation of simple RP-HPLC-PDA analytical protocol for zileuton assisted with Design of Experiments for robustness determination
TL;DR: In this article, a simple, rapid, sensitive, robust, stability-indicating RP-HPLC-PDA analytical protocol was developed and validated for the analysis of zileuton racemate in bulk and in tablet formulation.
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Exploring 2D and 3D QSARs of benzimidazole derivatives as transient receptor potential melastatin 8 (TRPM8) antagonists using MLR and kNN-MFA methodology
Kamlendra Singh Bhadoriya,Narender K. Kumawat,Suvarna V. Bhavthankar,Mandar H. Avchar,Dinesh M. Dhumal,Savita D. Patil,Shailesh V. Jain +6 more
TL;DR: The information rendered by 2D- and 3D-QSAR models may lead to a better understanding of structural requirements of cTRPM8 antagonists and also can help in the design of novel potent cTR PM8 antagonists.
Quantitative determination of Moxifloxacin hydrochloride in bulk and ophthalmic solution by UV-spectrophotometry and first orderderivative using area under curve
TL;DR: In this article, two simple, quick and economical methods, zero-order UV-Spectrophotometric (Method I) and first-order derived spectrophotometry (Method II) using area under curve (AUC) technique have been developed for routine analysis of MOX in bulk and ophthalmic solution.
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An ionizable supramolecular dendrimer nanosystem for effective siRNA delivery with a favorable safety profile
Dinesh M. Dhumal,Wenjun Lan,Ling Ding,Yifan Jiang,Zhenbin Lyu,Erik Laurini,Domenico Marson,Aura Tintaru,Nelson Dusetti,Suzanne Giorgio,Juan L. Iovanna,Sabrina Pricl,Sabrina Pricl,Ling Peng +13 more
TL;DR: An ionizable supramolecular dendrimer vector, formed via self-assembly of a small amphiphilic d endrimer, as an effective siRNA delivery system with a favorable safety profile, outperforming the gold standard vector, Lipofectamine 2000.