D
Dipak K. Das
Researcher at University of Connecticut
Publications - 329
Citations - 18415
Dipak K. Das is an academic researcher from University of Connecticut. The author has contributed to research in topics: Ischemia & Resveratrol. The author has an hindex of 75, co-authored 327 publications receiving 17708 citations. Previous affiliations of Dipak K. Das include Jawaharlal Nehru University & Baystate Medical Center.
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Journal ArticleDOI
Transgenic mice overexpressing glutathione peroxidase are resistant to myocardial ischemia reperfusion injury.
Tetsuya Yoshida,Masazumi Watanabe,Daniel T. Engelman,Richard M. Engelman,James A. Schley,Nilanjana Maulik,Ye-Shih Ho,Terry D. Oberley,Dipak K. Das +8 more
TL;DR: The results of this study indicate that increased GSHPx-1 expression renders the heart more resistant to myocardial ischemia reperfusion injury.
Book ChapterDOI
Antioxidant effectiveness in ischemia-reperfusion tissue injury
Dipak K. Das,Nilanjana Maulik +1 more
TL;DR: Much evidence supports the formation of toxic oxygen metabolites in ischemic reperfused tissue as a result of an excess production of oxygen free radicals and a decrease in antioxidant defenses.
Journal ArticleDOI
Direct scavenging of free radicals by captopril, an angiotensin converting enzyme inhibitor.
TL;DR: Results indicate that captopril is an extremely potent free radical scavenger, scavenging power being as effective as superoxide dismutase (SOD) against O2-, or dimethylthiourea against OH.
Journal ArticleDOI
Cardioprotection by adaptation to ischaemia augments autophagy in association with BAG-1 protein.
Narasimman Gurusamy,Istvan Lekli,Nikolai V. Gorbunov,Mihaela Gherghiceanu,Laurenciu M. Popescu,Dipak K. Das +5 more
TL;DR: Results clearly indicate that myocardial protection elicited by adaptation is mediated at least in part via up‐regulation of autophagy in association with BAG‐1 protein.
Journal ArticleDOI
Resveratrol, a polyphenol found in wine, reduces ischemia reperfusion injury in rat kidneys.
Luca Giovannini,Massimiliano Migliori,Biancamaria Longoni,Dipak K. Das,A. A. E. Bertelli,Vincenzo Panichi,C Filippi,Aldo Bertelli +7 more
TL;DR: The results suggest that resveratrol reduced the renal ischemia reperfusion injury through a nitric oxide-dependent mechanism.