D
Domenico Franco Merlo
Researcher at National Cancer Research Institute
Publications - 105
Citations - 4498
Domenico Franco Merlo is an academic researcher from National Cancer Research Institute. The author has contributed to research in topics: Population & Environmental exposure. The author has an hindex of 32, co-authored 103 publications receiving 3683 citations. Previous affiliations of Domenico Franco Merlo include University of Genoa.
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Journal ArticleDOI
Effect of Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia: A Randomized Clinical Trial.
Carlo Salvarani,Giovanni Dolci,Marco Massari,Domenico Franco Merlo,Silvio Cavuto,Luisa Savoldi,Paolo Bruzzi,Fabrizio Boni,Luca Braglia,Caterina Turrà,Pier Ferruccio Ballerini,Roberto Sciascia,Lorenzo Zammarchi,Ombretta Para,Pier Giorgio Scotton,Walter O Inojosa,Viviana Ravagnani,Nicola Duccio Salerno,Pier Paolo Sainaghi,Alessandro Brignone,Mauro Codeluppi,Elisabetta Teopompi,Maurizio Milesi,Perla Bertomoro,Norbiato Claudio,Mario Salio,Marco Falcone,Marco Falcone,Giovanni Cenderello,Lorenzo Donghi,Valerio Del Bono,Paolo Luigi Colombelli,Andrea Angheben,Angelina Passaro,Giovanni Secondo,Renato Pascale,Ilaria Piazza,Nicola Facciolongo,Massimo Costantini +38 more
TL;DR: This randomized clinical trial of hospitalized adult patients with COVID-19 pneumonia and Pao2/Fio2 ratio between 200 and 300 mm Hg who received tocilizumab found no benefit on disease progression was observed compared with standard care, and further blinded, placebo-controlled randomized clinical trials are needed.
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Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001): an international, open-label, randomised, controlled, phase 3, multicentre trial.
Alessandro Gronchi,Stefano Ferrari,Vittorio Quagliuolo,Javier Martin Broto,Antonio López Pousa,Giovanni Grignani,Umberto Basso,Jean-Yves Blay,Oscar Tendero,Robert Diaz Beveridge,Virginia Ferraresi,Iwona Lugowska,Domenico Franco Merlo,Valeria Fontana,Emanuela Marchesi,Davide Maria Donati,Elena Palassini,Emanuela Palmerini,Rita De Sanctis,Carlo Morosi,Silvia Stacchiotti,Silvia Bagué,Jean Michelle Coindre,Angelo Paolo Dei Tos,Piero Picci,Paolo Bruzzi,Paolo G. Casali +26 more
TL;DR: This international, open-label, randomised, controlled, phase 3, multicentre trial aimed to show the superiority of the neoadjuvant administration of histotype-tailored regimen to standard chemotherapy.
Journal ArticleDOI
Cancer incidence in pet dogs: findings of the Animal Tumor Registry of Genoa, Italy.
Domenico Franco Merlo,L. Rossi,C. Pellegrino,Marcello Ceppi,U. Cardellino,C. Capurro,A. Ratto,P. L. Sambucco,V. Sestito,G. Tanara,Vittorio Bocchini +10 more
TL;DR: Because a biopsy specimen was required to make a cancer diagnosis, cancer rates for internal organs cancers, such as respiratory and digestive tract cancers, may have been underestimated in the study population.
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Children's exposure to environmental pollutants and biomarkers of genetic damage. II. Results of a comprehensive literature search and meta-analysis
Monica Neri,Donatella Ugolini,Donatella Ugolini,Stefano Bonassi,Alexandra Fucic,Nina Holland,Lisbeth E. Knudsen,Radim J. Sram,Marcello Ceppi,Vittorio Bocchini,Domenico Franco Merlo +10 more
TL;DR: Future research and biomonitoring programs on children would greatly benefit from the inclusion of selected biomarkers that could provide biologically based evidence for the identification of intervention priorities in environmental health.
Journal ArticleDOI
Risk for Secondary Thyroid Carcinoma After Hematopoietic Stem-Cell Transplantation: An EBMT Late Effects Working Party Study
Amnon Cohen,Attilio Rovelli,Domenico Franco Merlo,Maria Teresa Van Lint,Edoardo Lanino,Dorine Bresters,Marcello Ceppi,Vittorio Bocchini,André Tichelli,Gérard Socié +9 more
TL;DR: Long-term survivors of HSCT are at risk for STCs, and results should promote efforts in screening for early detection and treatment guidelines of secondary thyroid cancer after HSCT, especially in patients who receive transplants during childhood and adolescence.