Pier Giorgio Scotton

TL;DR: This randomized clinical trial of hospitalized adult patients with COVID-19 pneumonia and Pao2/Fio2 ratio between 200 and 300 mm Hg who received tocilizumab found no benefit on disease progression was observed compared with standard care, and further blinded, placebo-controlled randomized clinical trials are needed.

TL;DR: In patients presenting with septic shock, absence of source control correlated with mortality rates above 60 % irrespective of administration of an adequate antifungal therapy, and in patients with septic shock, source control is fundamental.

TL;DR: From the multivariate analysis, congestive heart failure, stroke, prosthetic valve infection, S. aureus, and health care-associated acquisition were independently associated with increased in-hospital mortality, while surgery was associated with decreased mortality.

TL;DR: A genome-wide association study meta-analysis of up to 125,584 cases and over 2.5 million control individuals across 60 studies from 25 countries reveals compelling insights regarding disease susceptibility and severity.

TL;DR: Combined computed tomography and fluorodeoxyglucose positron emission tomography is a potentially promising diagnostic tool for several infectious conditions and it has also been employed in patients with prosthetic valve endocarditis but data are still scant.