N
Nina Holland
Researcher at University of California, Berkeley
Publications - 185
Citations - 15739
Nina Holland is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: DNA methylation & Population. The author has an hindex of 61, co-authored 178 publications receiving 13519 citations. Previous affiliations of Nina Holland include Lawrence Berkeley National Laboratory & University of California, San Francisco.
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Journal ArticleDOI
HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures.
Michael Fenech,Wushou P. Chang,Micheline Kirsch-Volders,Nina Holland,Stefano Bonassi,Errol Zeiger +5 more
TL;DR: Criteria for scoring micron nuclei and nucleoplasmic bridges in binucleated cells in the cytokinesis-block micronucleus assay for isolated human lymphocyte cultures are described in detail and will assist in the development of a procedure for calibrating scorers and laboratories so that results from different laboratories may be more comparable in the future.
Journal ArticleDOI
An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans.
Stefano Bonassi,Ariana Znaor,Marcello Ceppi,Cecilia Lando,Wushou P. Chang,Nina Holland,Micheline Kirsch-Volders,Errol Zeiger,Sadayuki Ban,Sadayuki Ban,Roberto Barale,Maria Paola Bigatti,Claudia Bolognesi,Antonina Cebulska-Wasilewska,Eleonora Fabianova,Alexandra Fucic,Lars Hagmar,Gordana Joksić,Antonietta Martelli,Lucia Migliore,Ekaterina Mirkova,Maria Rosaria Scarfì,Andrea Zijno,Hannu Norppa,Michael Fenech +24 more
TL;DR: Preliminary evidence is provided that MN frequency in PBL is a predictive biomarker of cancer risk within a population of healthy subjects and in all national cohorts and for all major cancer sites.
Journal ArticleDOI
DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
Bonnie R. Joubert,Janine F. Felix,Paul Yousefi,Kelly M. Bakulski,Allan C. Just,Carrie V. Breton,Sarah E. Reese,Christina A. Markunas,Christina A. Markunas,Rebecca C Richmond,Cheng-Jian Xu,Leanne K. Küpers,Sam S. Oh,Cathrine Hoyo,Olena Gruzieva,Cilla Söderhäll,Lucas A. Salas,Nour Baïz,Hongmei Zhang,Johanna Lepeule,Carlos Ruiz,Symen Ligthart,Tianyuan Wang,Jack A. Taylor,Liesbeth Duijts,Gemma C Sharp,Soesma A Jankipersadsing,Roy Miodini Nilsen,Ahmad Vaez,Ahmad Vaez,M. Daniele Fallin,Donglei Hu,Augusto A. Litonjua,Bernard F. Fuemmeler,Karen Huen,Juha Kere,Inger Kull,Monica Cheng Munthe-Kaas,Ulrike Gehring,Mariona Bustamante,Marie José Saurel-Coubizolles,Bilal M. Quraishi,Jie Ren,Jörg Tost,Juan R. González,Marjolein J. Peters,Siri E. Håberg,Zongli Xu,Joyce B. J. van Meurs,Tom R. Gaunt,Marjan Kerkhof,Eva Corpeleijn,Andrew P. Feinberg,Celeste Eng,Andrea A. Baccarelli,Sara E. Benjamin Neelon,Asa Bradman,Simon Kebede Merid,Anna Bergström,Zdenko Herceg,Hector Hernandez-Vargas,Bert Brunekreef,Mariona Pinart,Barbara Heude,Susan Ewart,Jin Yao,Nathanaël Lemonnier,Oscar H. Franco,Michael C. Wu,Albert Hofman,Albert Hofman,Wendy L. McArdle,Pieter van der Vlies,Fahimeh Falahi,Matthew W. Gillman,Lisa F. Barcellos,Ashok Kumar,Ashok Kumar,Ashok Kumar,Magnus Wickman,Magnus Wickman,Stefano Guerra,Marie-Aline Charles,John W. Holloway,Charles Auffray,Henning Tiemeier,George Davey Smith,Dirkje S. Postma,Marie-France Hivert,Brenda Eskenazi,Martine Vrijheid,Hasan Arshad,Josep M. Antó,Abbas Dehghan,Wilfried Karmaus,Isabella Annesi-Maesano,Jordi Sunyer,Akram Ghantous,Göran Pershagen,Nina Holland,Susan K. Murphy,Dawn L. DeMeo,Esteban G. Burchard,Christine Ladd-Acosta,Harold Snieder,Wenche Nystad,Gerard H. Koppelman,Caroline L Relton,Vincent W. V. Jaddoe,Allen J. Wilcox,Erik Melén,Erik Melén,Stephanie J. London +112 more
TL;DR: This large scale meta-analysis of methylation data identified numerous loci involved in response to maternal smoking in pregnancy with persistence into later childhood and provide insights into mechanisms underlying effects of this important exposure.
Journal ArticleDOI
The HUman MicroNucleus Project--An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans.
TL;DR: The extent to which micronucleus frequency is a valid biomarker of ageing and risk for diseases such as cancer is determined.
Journal ArticleDOI
Association of in Utero Organophosphate Pesticide Exposure and Fetal Growth and Length of Gestation in an Agricultural Population
Brenda Eskenazi,Kim G. Harley,Asa Bradman,Erin Weltzien,Nicholas P. Jewell,Dana B. Barr,Clement E. Furlong,Nina Holland +7 more
TL;DR: These associations with gestational age may be biologically plausible given that organophosphate pesticides depress cholinesterase and acetylcholine stimulates contraction of the uterus, and despite these observed associations, the rate of preterm delivery in this population was lower than in a U.S. reference population.