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Don S. Minckler

Researcher at University of California, Irvine

Publications -  149
Citations -  7292

Don S. Minckler is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Intraocular pressure & Glaucoma. The author has an hindex of 46, co-authored 143 publications receiving 6805 citations. Previous affiliations of Don S. Minckler include Armed Forces Institute of Pathology & University of Washington.

Papers
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Journal Article

Orthograde and retrograde axoplasmic transport during acute ocular hypertension in the monkey.

TL;DR: Serial reconstructions of radioautographs and peroxidase-reacted sections of the optic nerve heads demonstrated that the orthograde and retrograde transport obstructions were coincidental anatomically by light microscopy in the LS and occurred most prominently in the temporal quadrants of the nerve head.
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Aqueous shunts in glaucoma: a report by the American Academy of Ophthalmology.

TL;DR: Level I evidence indicates that there are no advantages to the adjunctive use of antifibrotic agents or systemic corticosteroids with currently available shunts, and aqueous shunts seem to have benefits comparable with those of trabeculectomy in the management of complex glaucoma.
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Clinical experience with the single-plate Molteno implant in complicated glaucomas

TL;DR: Ninety patients with medically uncontrollable glaucomas and poor surgical prognoses received single-plate Molteno implants without postoperative adjunctive systemic antifibrosis therapy without assessment of intraocular pressure (IOP) or visual acuity outcome.
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Clinical Results with the Trabectome for Treatment of Open-Angle Glaucoma

TL;DR: The Trabectome seems to offer a safe and effective method of lowering IOP in OAG and remained stable in all patients beyond 3 weeks postoperatively except one, not sutured at surgery, who had a late hyphema probably associated with corneal wound gaping after accidental blunt trauma.
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Which Is Better? One or Two?: A Randomized Clinical Trial of Single-plate versus Double-plate Molteno Implantation for Glaucomas in Aphakia and Pseudophakia

TL;DR: Double-plate Molteno implantation more frequently affords IOP control than single-plates, however, double plates are associated with greater risks of choroidal hemorrhages and/or effusions, corneal decompensation, flat anterior chambers, and phthisis bulbi.