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Showing papers in "Ophthalmology in 1988"


Journal ArticleDOI
TL;DR: It is confirmed that the death of a substantial proportion of optic nerve fibers precedes detectable visual field loss and that no fiber size was completely spared at any stage of atrophy.

558 citations


Journal ArticleDOI
TL;DR: Without exception, within a period of 1 year the intraocular silicone oil showed some degree of emulsification, suggesting that the physicochemical characteristics of the oil injected may be an important variable in long-term complications.

410 citations


Journal ArticleDOI
TL;DR: In this article, the authors reviewed 158 eyes with evolving or completed idiopathic macular holes and found that prefoveal vitreous cortex contraction is probably the cause of macular hole development.

385 citations


Journal ArticleDOI
TL;DR: It is believed that mitomycin eye drops is a safe and effective adjunct to surgical excision in the treatment of primary or recurrent pterygia, or both.

323 citations


Journal ArticleDOI
TL;DR: Using an excimer laser at 193 nm, 3-mm diameter discs were ablated from the optical zone of monkey corneas at a variety of depths up to 130 micron and showed a normal morphology in this layer with the exception that basal cells were slightly more elevated particularly at the disc margins where the epithelium contained more cell layers.

286 citations


Journal ArticleDOI
TL;DR: Both intraobserver and interobserver agreement for horizontal and vertical cup:disc ratios and width of the narrowest remaining neuroretinal rim on stereo, color, fundus photographs were best for glaucoma patients followed by ocular hypertensives and controls.

268 citations


Journal ArticleDOI
TL;DR: Six complications, of retrobulbar injections documented by fundus photography and fluorescein angiography are described and alternative techniques that might decrease the incidence of complications associated with retrobul bar injections are discussed.

266 citations


Journal ArticleDOI
TL;DR: It is demonstrated that the vitreous may play a role in diabetic macular edema by assessing retrospectively clinical records of 76 patients (125 eyes) 60 years of age or older with diabetic retinopathy who had undergone a Vitreous examination.

264 citations


Journal ArticleDOI
TL;DR: In this paper, the most sensitive indicators of optic nerve dysfunction appeared to be visual-evoked potentials and color vision in dysthyroid optic neuropathy patients and apical orbital crowding was a characteristic feature.

255 citations


Journal ArticleDOI
TL;DR: The findings indicate that carriers of the retinoblastoma gene have an increased incidence of second tumors, and that the incidence rate is further increased in patients who receive radiation therapy.

250 citations


Journal ArticleDOI
TL;DR: Ninety patients with medically uncontrollable glaucomas and poor surgical prognoses received single-plate Molteno implants without postoperative adjunctive systemic antifibrosis therapy without assessment of intraocular pressure (IOP) or visual acuity outcome.

Journal ArticleDOI
TL;DR: The authors conducted a hospital-based study to ascertain basic, descriptive epidemiologic information about ocular trauma in an urban setting and found that a disproportionate burden of severe ocular injury was borne by those less than 15 years of age.

Journal ArticleDOI
TL;DR: The percentage of patients with a visual outcome of 20/40 or better has remained the same, whereas the incidence of enucleation has diminished, compared with other large series of intraocular foreign bodies reported before the development of vitreous microsurgical techniques.

Journal ArticleDOI
TL;DR: Results of cytologic examination appeared to be more accurate than those of conventional lymphocyte surface marker studies in the diagnosis of an intraocular lymphoma patients who initially presented with either ocular or central nervous system (CNS) disease.

Journal ArticleDOI
TL;DR: The 4-year incidence of blindness and vision loss was examined in a population-based study of diabetes mellitus and was associated with older age, more severe retinopathy, and presence of macular edema in the three groups.

Journal ArticleDOI
TL;DR: The authors report 19 cases of exogenous fungal endophthalmitis managed between 1969 and 1986 that developed after ocular surgery, after trauma, by intraocular spread from fungal keratitis, after therapeutic keratoplasty for ker atitis, and by spontaneous infection of a filtration bleb.

Journal ArticleDOI
TL;DR: There was no clear relationship between toxin dose and the amount of spasm reduction or duration of response, and average duration of beneficial effect remained constant from the first through the twelfth injections.

Journal ArticleDOI
TL;DR: Peripheral corneal diseases that probably represent a hypersensitivity reaction to exogenous antigens include catarrhal infiltrates and ulcers and phlyctenules, and Experimental models suggest that hypersensitivity to Staphylococcus aureus cell wall antigen may be important to their immunopathogenesis

Journal ArticleDOI
TL;DR: The authors' experience with these 30 intravitreal injections indicates that the procedure is safe and effective both as an alternative to intravenous ganciclovir therapy in myelosuppressed patients and as a supplement to intravenously therapy in uncontrolled CMV retinitis.

Journal ArticleDOI
TL;DR: There was a statistically significant difference in the amount of decentration in the three fixation groups studied and capsular fixation provides the best and most consistent centration compared with fixation of both loops in the ciliary sulcus or asymmetrical fixation with only one loop in the capsular sac.

Journal ArticleDOI
TL;DR: In this article, 60 patients were treated by some combination of cryotherapy and surgery with an average follow-up of 3.3 years for one of the following diseases: focal or diffuse flat conjunctival primary acquired melanosis (PAM) with atypia but without a nodule of melanoma.

Journal ArticleDOI
TL;DR: Although significant hue discrimination and contrast sensitivity deficits were observed in both groups of diabetic patients, contrast sensitivity was abnormal more frequently than hue discrimination, and the hue discrimination deficits, but not the contrast sensitivity abnormalities, were correlated with the patients' hemoglobin A1 level.

Journal ArticleDOI
TL;DR: The Molteno implant may prove useful in the management of medically uncontrollable glaucoma following penetrating keratoplasty; however, there appears to be a substantial risk of postoperative graft rejection.

Journal ArticleDOI
TL;DR: Results of pathologic examination of the corneal buttons from each patient after penetrating keratoplasty confirmed granular deposits in the anterior third of the stroma, and the histochemical pattern of staining of the granular material by a series of lectins was similar to that present in corneas with lattice dystrophy.

Journal ArticleDOI
TL;DR: The results suggest that the combined procedure gives excellent visual rehabilitation and IOP control in the majority of patients included in this analysis.

Journal ArticleDOI
TL;DR: In this article, aqueous humor flow and the permeability of the blood-aqueous barrier were measured by fluorophotometry. And the results showed that apraclonidine hydrochloride (ALO 2145) had little, if any, effect on the flow rate.

Journal ArticleDOI
TL;DR: In an effort to achieve the early postoperative safety and stability provided by trabeculectomy plus the late lower intraocular pressure (IOP) advantages of full-thickness glaucoma filtration surgery, 43 eyes of 38 patients with chronic open-angle glaucolysis had laser suture lysis after primary trabECUlectomy.

Journal ArticleDOI
TL;DR: The success rate of contact lens fitting and rate of progression to keratoplasty were evaluated for 115 consecutive patients with keratoconus, finding that special design, bispheric lenses were required in 125 of these 165 eyes and frequent lens changes were necessary.

Journal ArticleDOI
TL;DR: The data suggest that laser photocoagulation may be acutely beneficial in the prevention or management of retinal tears and detachments.

Journal ArticleDOI
TL;DR: Cowden's disease, or multiple hamartoma syndrome, is a rare genodermatosis associated with increased rates of cancer of the breast and thyroid as well as benign tumors and hamartomas of multiple organ systems.