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Showing papers in "Ophthalmology in 1992"


Journal ArticleDOI
TL;DR: In this article, the relationship between retinal drusen, retinal pigmentary abnormalities, and macular degeneration to age and sex was studied in 4926 people between the ages of 43 and 86 years who participated in the Beaver Dam Eye Study.

1,722 citations


Journal ArticleDOI
TL;DR: The prevalence of diabetic retinopathy was examined in people with newly discovered noninsulin-dependent diabetes mellitus (NIDDM) (n = 50) and in those with previously diagnosed diabetes.

1,397 citations


Journal ArticleDOI
TL;DR: The prevalence of open-angle glaucoma in Beaver Dam is similar to that in other white populations, and findings from this study re-emphasize the notion that estimates of glauca prevalence should be based on assessing multiple risk indicators.

976 citations


Journal ArticleDOI
TL;DR: If mitomycin is used, the lowest possible concentration should be applied for the shortest time period in an effort to avoid these complications and the authors urge extreme caution in the use of this medication.

639 citations


Journal ArticleDOI
TL;DR: The evaluation of cup-to-disc ratio or of the nerve fiber layer appearance in the initial photograph taken 5 years before field loss were equally predictive of future field damage.

589 citations


Journal ArticleDOI
TL;DR: The Beaver Dam Eye Study as discussed by the authors was designed to estimate the prevalence and severity of lens opacities in a rural community in the United States, and it was found that the frequency of late cataract increased consistently with age.

583 citations


Journal ArticleDOI
TL;DR: Vitreous surgery can improve the visual prognosis of some eyes with diabetic macular traction and edema associated with a thickened and taut posterior hyaloid with a mild epimacular membrane.

536 citations


Journal ArticleDOI
TL;DR: It is suggested that intraoperative MMC may be a viable alternative to postoperative 5-FU, with lower overall intraocular pressures, decreased dependence on postoperative ocular antihypertensive medications, and decreased corneal toxicity.

462 citations


Journal ArticleDOI
TL;DR: In this paper, the efficacy and safety of excimer laser photorefractive keratectomy was evaluated in 120 patients with follow-up, 12 to 22 months, and mean, 18 months.

378 citations


Journal ArticleDOI
TL;DR: The ability of experts to reliably evaluate the optic disc within themselves is confirmed and the need for developing standardized methods for interobserver evaluation of the optic Disc in glaucoma is emphasized.

315 citations


Journal ArticleDOI
TL;DR: Key predictors of graft failure were an indication for graft other than keratoconus or corneal dystrophy; a failed previous graft; aphakia; inflammation at the time of graft; presence of an anterior chamber or iris-clip intraocular lens; graft size outside the range of 7.0 to 7.9 mm diameter.

Journal ArticleDOI
TL;DR: There is a statistically significant increase in the risk of retinal detachment or break in those patients who undergo capsulotom after cataract extraction, and capsulotomy should be deferred until the patient's impairment caused by capsular opacification warrants the increased risk ofretinal complications associated with performance of Capsulotomy.

Journal ArticleDOI
TL;DR: In this paper, the authors performed a prospective randomized study of 60 patients to determine if the local application of TGF-β 2 to the edge of the macular hole can reproducibly induce flattening of the surrounding neurosensory detachment.

Journal ArticleDOI
TL;DR: Some patients with subfoveal CNV appear to benefit from surgical removal, and longer-term follow-up and refined case selection are required before this approach can be widely recommended.

Journal ArticleDOI
TL;DR: There is a strong suggestion of a causal relationship between ultraviolet light exposure and the development of pterygia during the early years of life and the cumulative exposure over the next 2 to 3 decades in occupations in which there is a high component of reflected ultraviolet light.

Journal ArticleDOI
TL;DR: PHMB is a promising new treatment for this infection and in 5 of 6 cases, complete resolution of inflammation followed the introduction of PHMB, unlike propamidine or neomycin.

Journal ArticleDOI
TL;DR: The ability of a brief exposure to MMC to improve filtration surgery may be due to an almost complete inhibition of proliferation, due to sustained tissue binding, effects on other components of wound healing, such as cell migration and extracellular matrix production, or effects on the vasculature.

Journal ArticleDOI
TL;DR: Double-plate Molteno implantation more frequently affords IOP control than single-plates, however, double plates are associated with greater risks of choroidal hemorrhages and/or effusions, corneal decompensation, flat anterior chambers, and phthisis bulbi.

Journal ArticleDOI
TL;DR: It is demonstrated that chronic application of a commercial preparation of timolol maleate damaged the ocular surface, especially the mucus layer of the tear film.

Journal ArticleDOI
TL;DR: Using cultured cells as well as normal rabbit corneas, the staining differences between rose bengal and fluorescein are characterized and correlate with the differences in their chemical structures to help interpret the clinical staining properties of these two dyes and enhance the understanding of the pathogenesis of various ocular surface disorders.

Journal ArticleDOI
TL;DR: In this article, the authors showed that subfoveal neovascularization can be successfully removed with preservation of fovea vision in ocular histoplasmosis syndrome (POHS) and age-related macular degeneration (ARMD), at least for the short term.

Journal ArticleDOI
TL;DR: In this paper, the authors conducted a case-control study of risk factors for retinal vein occlusions using 87 patients with vein occlation, chosen randomly from photographic files from their institution between 1985 and 1990, and a control group of 85 subjects 38 years of age or older, who were randomly selected from the records of two general ophthalmologists in the department.

Journal ArticleDOI
TL;DR: Ultrasound biomicroscopy proved a valuable new noninvasive technique in the evaluation of anterior segment tumors and compared favorably with low-power microscopy.

Journal ArticleDOI
TL;DR: Although these implants are relatively inert and develop a fibrous capsule walling them off from the surrounding orbit, they remain foreign bodies and are thus subject to possible complications at any time.

Journal ArticleDOI
TL;DR: Treatment with low-dose methotrexate appears to be effective therapy for steroid-resistant ocular inflammatory disease.

Journal ArticleDOI
TL;DR: This new therapeutic modality, which combines endoscopic visualization of the ciliary processes with diode laser photocoagulation, can be effective in the management of intractable neovascular glaucoma.

Journal ArticleDOI
TL;DR: Lower birth weight and increasing severity of retinopathy of prematurity (ROP), anisometropia, astigmatism, and the presence of posterior pole residua from ROP also were associated with a higher incidence of myopia and high myopia.

Journal ArticleDOI
TL;DR: In this paper, the age distribution, frequency, and correlation among histologic macular changes, including formation of a basal laminar deposit, drusen, and thickening and calcification of Bruch's membrane, were studied by light microscopy.

Journal ArticleDOI
TL;DR: This technique offers enhanced image resolution, the possibility of direct qualitative comparison with fluorescein angiography, image archiving, hard-copy generation, and tracing capabilities to plan laser treatment strategies and monitor the adequacy of laser therapy after surgery.

Journal ArticleDOI
TL;DR: Observations support the central hypothesis concerning biophysical changes in Bruch's membrane with age and the potential importance of fluorescein angiography in the characterization of Bruch’s membrane deposits.