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Donal J. Brennan

Researcher at Mater Misericordiae University Hospital

Publications -  150
Citations -  7861

Donal J. Brennan is an academic researcher from Mater Misericordiae University Hospital. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 42, co-authored 129 publications receiving 6598 citations. Previous affiliations of Donal J. Brennan include University College Dublin & Mater Health Services.

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methylation and regulates tumor growth in hematopoietic malignancies

TL;DR: The data show that SOX11 is not a bystander but an active and central regulator of cellular growth, as both siRNA-mediated knock-down and ectopic overexpression of SoX11 resulted in altered proliferation.
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Quality of life following minimally invasive hysterectomy compared to abdominal hysterectomy: A metanalysis.

TL;DR: MIS hysterectomy is associated with improved QoL in the short term post-operative phase compared to AH both for benign disease and endometrial cancer.
Journal Article

Carbonic anhydrase IX is a new independent prognostic marker in pre-menopausal breast cancer patients with 1 to 3 positive lymph nodes

TL;DR: It is suggested that inhibition of CA IX may be a useful method of increasing the radiosensitivity of such tumors in patients with one to three positive lymph nodes as all of these patients received locoregional radiotherapy.
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Short-term outcomes in older patients with peritoneal malignancy treated with cytoreductive surgery and HIPEC: Experience with 245 patients from a national centre.

TL;DR: In this paper, a retrospective review of a prospective database of all patients who underwent CRS with HIPEC in a single institution over seven years was performed, and a comparative analysis of outcomes in patients under 65 undergoing CRS and HIPEC with patients ≥ 65 years were performed.