C
Carl A.K. Borrebaeck
Researcher at Lund University
Publications - 382
Citations - 14100
Carl A.K. Borrebaeck is an academic researcher from Lund University. The author has contributed to research in topics: Antibody & Antigen. The author has an hindex of 64, co-authored 378 publications receiving 13382 citations. Previous affiliations of Carl A.K. Borrebaeck include Osaka University & Karolinska University Hospital.
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Method of producing human monoclonal antibodies and kit therefor
TL;DR: In this article, a method for the removal of undesired cells from human lymphocyte containing cell populations is disclosed, where use is made of lysosomotropic agents which are caused to act in vitro on human lymphocytes.
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Recombining germline-derived CDR sequences for creating diverse single- framework antibody libraries
Eskil Söderlind,Leif Strandberg,Pernilla Jirholt,Norihiro Kobayashi,Vessela Alexeiva,Anna Maria Åberg,Anna Nilsson,Bo Jansson,Mats Ohlin,Christer Wingren,Lena Danielsson,Roland Carlsson,Carl A.K. Borrebaeck +12 more
TL;DR: A single-chain Fv antibody library that permits human complementarity-determining region (CDR) gene fragments of any germline to be incorporated combinatorially into the appropriate positions of the variable-region frameworks VH-DP47 and VL-DPL3 is constructed.
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Antibodies in diagnostics - from immunoassays to protein chips.
TL;DR: Recent opportunities presented by antibodies as diagnostic tools are reviewed, including microarray analysis of the proteome using protein chips.
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Precision diagnostics : moving towards protein biomarker signatures of clinical utility in cancer
TL;DR: Progress is being made in identifying protein biomarker signatures of clinical utility, using blood-based proteomics, using single to multiplex biomarkers that can provide significantly increased diagnostic accuracy.
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ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome
Michael J. Taussig,Oda Stoevesandt,Carl A.K. Borrebaeck,Andrew Bradbury,Dolores J. Cahill,Christian Cambillau,Antoine de Daruvar,Stefan Dübel,Jutta Eichler,Ronald Frank,Toby J. Gibson,David E. Gloriam,Larry Gold,Friedrich W. Herberg,Henning Hermjakob,Jörg D. Hoheisel,Thomas O. Joos,Olli Kallioniemi,Manfred Koegl,Zoltán Konthur,Bernhard Korn,Elisabeth Kremmer,Sylvia Krobitsch,Ulf Landegren,Silvère M. van der Maarel,John McCafferty,Serge Muyldermans,Per-Åke Nygren,Sandrine Palcy,Andreas Plückthun,Bojan Polić,Michael Przybylski,Petri Saviranta,Alan Sawyer,David James Sherman,Arne Skerra,Markus F. Templin,Marius Ueffing,Mathias Uhlén +38 more
TL;DR: ProteomeBinders is a new European consortium aiming to establish a comprehensive resource of well-characterized affinity reagents, including but not limited to antibodies, for analysis of the human proteome.