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Dong-Bo Chen
Researcher at Academy of Military Medical Sciences
Publications - 3
Citations - 190
Dong-Bo Chen is an academic researcher from Academy of Military Medical Sciences. The author has contributed to research in topics: Embryonic stem cell & Stem cell. The author has an hindex of 3, co-authored 3 publications receiving 158 citations.
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Journal ArticleDOI
Mouse Embryonic Head as a Site for Hematopoietic Stem Cell Development
Zhuan Li,Yu Lan,Wenyan He,Dong-Bo Chen,Jun Wang,Fan Zhou,Yu Wang,Huayan Sun,Xianda Chen,Chunhong Xu,Sha Li,Yakun Pang,Guangzhou Zhang,Liping Yang,Lingling Zhu,Ming Fan,Aijia Shang,Zhenyu Ju,Lingfei Luo,Yu-Qiang Ding,Wei Guo,Weiping Yuan,Xiao Yang,Bing Liu,Bing Liu,Bing Liu +25 more
TL;DR: It is concluded that the mouse embryonic head is a previously unappreciated site for HSC emergence within the developing embryo, and the physiological contribution of cerebrovascular endothelium to postnatal HSCs and multilineage hematopoiesis is revealed.
Journal ArticleDOI
Migration of dorsal aorta mesenchymal stem cells induced by mouse embryonic circulation.
Xinlong Yan,Yu Lan,Xiao-Yan Wang,Wenyan He,Huiyu Yao,Dong-Bo Chen,Jiaxiang Xiong,Jiao Gao,Zhuan Li,Guan Yang,Xiu-Sen Li,Yuan-Lin Liu,Jiyan Zhang,Bing Liu,Ning Mao +14 more
TL;DR: Results revealed that clonal MSCs developed in the mouse DA, and suggested that the embryonic circulation, in addition to its conventional transporting roles, could modulate migration of MSC during early embryogenesis.
Journal ArticleDOI
Generation of hematopoietic stem cells from purified embryonic endothelial cells by a simple and efficient strategy.
TL;DR: In this paper, an OP9-DL1-based co-culture system was developed to facilitate the HSC specification and/or expansion in mouse embryonic day 10.5 (E10.5) Tie2 + cells remarkably.