Y
Yu Wang
Publications - 2
Citations - 191
Yu Wang is an academic researcher. The author has contributed to research in topics: Endothelial stem cell & Embryonic stem cell. The author has an hindex of 2, co-authored 2 publications receiving 156 citations.
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Journal ArticleDOI
Mouse Embryonic Head as a Site for Hematopoietic Stem Cell Development
Zhuan Li,Yu Lan,Wenyan He,Dong-Bo Chen,Jun Wang,Fan Zhou,Yu Wang,Huayan Sun,Xianda Chen,Chunhong Xu,Sha Li,Yakun Pang,Guangzhou Zhang,Liping Yang,Lingling Zhu,Ming Fan,Aijia Shang,Zhenyu Ju,Lingfei Luo,Yu-Qiang Ding,Wei Guo,Weiping Yuan,Xiao Yang,Bing Liu,Bing Liu,Bing Liu +25 more
TL;DR: It is concluded that the mouse embryonic head is a previously unappreciated site for HSC emergence within the developing embryo, and the physiological contribution of cerebrovascular endothelium to postnatal HSCs and multilineage hematopoiesis is revealed.
Journal ArticleDOI
Endothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation
Yu Lan,Wenyan He,Zhuan Li,Yu Wang,Jun Wang,Jiao Gao,Weili Wang,Tao Cheng,Bing Liu,Bing Liu,Xiao Yang +10 more
TL;DR: The data for the first time identify a physiological suppressor that functions specifically during the transition of endothelial cells to hematopoietic progenitors and suggest that endothelial Smad4 is a crucial modulator of the subaortic microenvironment that controls the hematoietIC fate of the aortic endothelium.