D
Dongfang Meng
Researcher at Columbia University
Publications - 32
Citations - 1597
Dongfang Meng is an academic researcher from Columbia University. The author has contributed to research in topics: Epothilones & Ring (chemistry). The author has an hindex of 18, co-authored 31 publications receiving 1585 citations. Previous affiliations of Dongfang Meng include Kettering University & Albert Einstein College of Medicine.
Papers
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Journal ArticleDOI
Total Syntheses of Epothilones A and B
Dongfang Meng,Peter Bertinato,Aaron Balog,Dai Shi Su,Theodore M. Kamenecka,Erik J. Sorensen,Samuel J. Danishefsky +6 more
TL;DR: In this paper, a stereocontrolled total synthesis of the microtubule-stabilizing macrolides epothilones A (2) and B (3) has been achieved.
Journal ArticleDOI
Total Synthesis of (–)‐Epothilone B: An Extension of the Suzuki Coupling Method and Insights into Structure–Activity Relationships of the Epothilones
Dai Shi Su,Dongfang Meng,Dongfang Meng,Peter Bertinato,Aaron Balog,Erik J. Sorensen,Samuel J. Danishefsky,Samuel J. Danishefsky,Yu Huang Zheng,Ting-Chao Chou,Lifeng He,Susan Band Horwitz +11 more
Journal ArticleDOI
Remote effects in macrolide formation through ring-forming olefin metathesis : an application to the synthesis of fully active epothilone congeners
Dongfang Meng,Dai-Shi Su,Aaron Balog,Peter Bertinato,Erik J. Sorensen,Samuel J. Danishefsky,Yu-Huang Zheng,Ting-Chao Chou,Lifeng He,Susan Band Horwitz +9 more
Patent
Synthesis of epothilones intermediates thereto and analogues thereof
Samuel J. Danishefsky,Peter Bertinato,Dai-Shi Su,Dongfang Meng,Ting-Chao Chou,Theodore M. Kamenecka,Erik J. Sorensen,Aaron Balog,Kenneth A. Savin,Scott D. Kuduk,Christina Harris,Xiuguo Zhang,Joseph R. Bertino +12 more
TL;DR: In this paper, a convergent process for preparing epothilone A and B, desoxyepothilones B and C, and analogues thereof, useful in the treatment of cancer and cancer which has developed a multidrug-resistant phenotype is presented.