Donna J. Ingles

TL;DR: Although this small compound library contained only ATP‐site‐directed ligands, the application of this assay to large compound libraries has the potential to reveal previously unrecognized chemical scaffolds suitable for structure‐based design of CDK2 inhibitors with new mechanisms of action.

TL;DR: This is the first study demonstrating that vaccination of males with Gardasil induces HPV antibody levels at the oral cavity that correlate with circulating levels, and these levels were significantly correlated with serum levels.

TL;DR: Most EGLs develop following infection with HPV 6, 11, or 16, all of which could be prevented with the 4-valent HPV vaccine, according to a prospective analysis nested within the HPV Infection in Men study.

TL;DR: Prevalent oral HPV16 infections in men persisted longer than newly acquired infections, and persistence appeared to increase with age, which may explain the high prevalence of oral HPV observed at older ages.

TL;DR: The immune response to HPV vaccination in men ages 27-45 was comparable to that observed in younger men, in whom clinical efficacy was demonstrated and further trials to assess the efficacy of HPV vaccines to prevent persistent HPV infections in mid-adult men are needed.