D
Dorothea Besch
Researcher at University of Tübingen
Publications - 85
Citations - 3161
Dorothea Besch is an academic researcher from University of Tübingen. The author has contributed to research in topics: Visual acuity & Point mutation. The author has an hindex of 24, co-authored 83 publications receiving 2894 citations.
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Journal ArticleDOI
Subretinal electronic chips allow blind patients to read letters and combine them to words
Eberhart Zrenner,Karl Ulrich Bartz-Schmidt,H. Benav,Dorothea Besch,A. Bruckmann,Veit-Peter Gabel,Florian Gekeler,Udo Greppmaier,Alex Harscher,Steffen Kibbel,Johannes Koch,Akos Kusnyerik,Akos Kusnyerik,Tobias Peters,Katarina Stingl,Helmut G. Sachs,Alfred Stett,Peter Szurman,Barbara Wilhelm,Robert Wilke +19 more
TL;DR: These results demonstrate for the first time that subretinal micro-electrode arrays with 1500 photodiodes can create detailed meaningful visual perception in previously blind individuals.
Journal ArticleDOI
Artificial vision with wirelessly powered subretinal electronic implant alpha-IMS.
Katarina Stingl,Karl Ulrich Bartz-Schmidt,Dorothea Besch,Angelika Braun,A. Bruckmann,Florian Gekeler,Udo Greppmaier,Stephanie Hipp,Gernot Hörtdörfer,Christoph Kernstock,Assen Koitschev,Akos Kusnyerik,Akos Kusnyerik,Helmut G. Sachs,Andreas Schatz,Krunoslav Stingl,Tobias Peters,Barbara Wilhelm,Eberhart Zrenner +18 more
TL;DR: The data show that subretinal implants can restore visual functions that are useful for daily life in patients who are blind owing to untreatable forms of hereditary retinal degenerations.
Journal ArticleDOI
Subretinal Visual Implant Alpha IMS - Clinical trial interim report
Katarina Stingl,Karl Ulrich Bartz-Schmidt,Dorothea Besch,Caroline Chee,Charles L Cottriall,Florian Gekeler,Markus Groppe,Timothy L Jackson,Robert E MacLaren,Assen Koitschev,Akos Kusnyerik,James E. Neffendorf,János Németh,Mohamed Adheem Naser Naeem,Tobias Peters,James D. Ramsden,Helmut G. Sachs,Andrew Simpson,Mandeep S. Singh,Barbara Wilhelm,David Wong,Eberhart Zrenner +21 more
TL;DR: These results show that subretinal implants can restore very-low-vision or low vision in blind (light perception or less) patients with end-stage hereditary retinal degenerations.
Journal ArticleDOI
Spatial resolution and perception of patterns mediated by a subretinal 16-electrode array in patients blinded by hereditary retinal dystrophies.
Robert Wilke,Veit-Peter Gabel,Helmut G. Sachs,Karl-Ulrich Bartz Schmidt,Florian Gekeler,Dorothea Besch,Peter Szurman,Alfred Stett,Barbara Wilhelm,Tobias Peters,Alex Harscher,Udo Greppmaier,Steffen Kibbel,H. Benav,A. Bruckmann,Katarina Stingl,Akos Kusnyerik,Akos Kusnyerik,Eberhart Zrenner +18 more
TL;DR: Subretinal electric stimulation can yield reliable, predictable percepts, enabling blind persons to recognize shapes and discriminate different letters, and Stimulation paradigms must be optimized to further increase spatial resolution.
Journal ArticleDOI
Interim Results of a Multicenter Trial with the New Electronic Subretinal Implant Alpha AMS in 15 Patients Blind from Inherited Retinal Degenerations
Katarina Stingl,Ruth Schippert,Karl U. Bartz-Schmidt,Dorothea Besch,Charles L Cottriall,Thomas L Edwards,Florian Gekeler,Udo Greppmaier,Katja Kiel,Assen Koitschev,Laura Kühlewein,Robert E MacLaren,James D. Ramsden,Johann Roider,Albrecht Rothermel,Helmut G. Sachs,Greta S. Schröder,Jan Tode,Nicole Troelenberg,Eberhart Zrenner +19 more
TL;DR: Psychophysical and subjective data show that RETINA IMPLANT Alpha AMS is reliable, well tolerated and can restore limited visual functions in blind patients with degenerations of the outer retina.