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Dunhui Li

Researcher at Murdoch University

Publications -  22
Citations -  345

Dunhui Li is an academic researcher from Murdoch University. The author has contributed to research in topics: Parkinson's disease & Exon. The author has an hindex of 9, co-authored 18 publications receiving 219 citations. Previous affiliations of Dunhui Li include University of Western Australia & Shanghai Jiao Tong University.

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Diagnostic Accuracy of Transcranial Sonography of the Substantia Nigra in Parkinson's disease: A Systematic Review and Meta-analysis.

TL;DR: A systematic review of the literature and meta-analysis suggest that TCS has high diagnostic accuracy in the diagnosis of PD when compared to healthy control.
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Precision Medicine through Antisense Oligonucleotide-Mediated Exon Skipping.

TL;DR: The potential of therapeutic alternative splicing is discussed, with a particular focus on targeted exon skipping using Duchenne MD as an example, and new applications for other inherited rare diseases where redundant or dispensable exons may be amenable to exon-skipping ASO intervention as precision medicine are speculated.
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A community-based study of risk factors for probable rapid eye movement sleep behavior disorder.

TL;DR: It was found that lower education, presence of head injury, atrial fibrillation, hyperlipidemia, constipation, olfactory disturbance, and imbalance, use of alcoholic beverage, selective serotonin reuptake inhibitor, and benzodiazepine were associated with higher likelihood of having pRBD.
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Neurodegenerative diseases: a hotbed for splicing defects and the potential therapies.

TL;DR: A review of the current understanding of the effects alternative splicing has on neuronal differentiation, neuronal migration, synaptic maturation and regulation, as well as the impact on neurodegenerative diseases is provided in this article.
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Progress in the molecular pathogenesis and nucleic acid therapeutics for Parkinson's disease in the precision medicine era.

TL;DR: Progress in the use of antisense oligonucleotides, small interferingRNAs, short hairpin RNAs, aptamers, and microRNA‐based therapeutics to target critical elements in the pathogenesis of PD that could have the potential to modify disease progression are discussed.