E
Edmond J. LaVoie
Researcher at Rutgers University
Publications - 182
Citations - 8160
Edmond J. LaVoie is an academic researcher from Rutgers University. The author has contributed to research in topics: Topoisomerase & Cytotoxicity. The author has an hindex of 42, co-authored 178 publications receiving 7619 citations. Previous affiliations of Edmond J. LaVoie include San Antonio River Authority & National Pingtung University of Science and Technology.
Papers
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Journal ArticleDOI
Tumor-initiating activity of major in vivo metabolites of indeno[1, 2, 3-cd]pyrene on mouse skin
Joseph E. Rice,Thomas J. Hosted,Marianne C. DeFloria,Edmond J. LaVoie,Daniel L. Fischer,James C. Wiley +5 more
TL;DR: Results indicate that the principal metabolic activation pathways associated with the mutagenic activity of indeno[1,2,3-cd]pyrene are not related to its tumor-initiating activity on mouse skin.
Patent
Therapeutic hydroxypyridinones, hydroxypyrimidinones and hydroxypyridazinones
Edmond J. LaVoie,Joseph D. Bauman,Ajit K. Parhi,Hye Yeon Sagong,D. Patel,Eddy Arnold,Kalyan Das,Suyambu Kesava Vijayan +7 more
TL;DR: In this paper, the authors provide compounds of formula (I): and salts and prodrugs thereof thereof wherein R4, X1 and X2 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts and methods for their use in therapy.
Patent
Method for treating glaucoma ib
TL;DR: In this article, a method of treating or ameliorating or preventing glaucoma, decreasing intraocular pressure or improving or amemliorting ocular accommodation in an animal, including a human comprising administering an intra-ocular pressure decreasing or accommodation improving mount of a compound of the formula (I).
Journal ArticleDOI
Synthesis of the isomeric phenols and the trans-2,3-dihydrodiol of fluoranthene
Journal ArticleDOI
Effect of fluorine substitution on benzo[j]fluoranthene genotoxicity
TL;DR: It is suggested that fluorine substitution may significantly alter the intrinsic genotoxicity of the 4,5- and 9,10-dihydrodiol of B[j]F.