E
Edmond J. LaVoie
Researcher at Rutgers University
Publications - 182
Citations - 8160
Edmond J. LaVoie is an academic researcher from Rutgers University. The author has contributed to research in topics: Topoisomerase & Cytotoxicity. The author has an hindex of 42, co-authored 178 publications receiving 7619 citations. Previous affiliations of Edmond J. LaVoie include San Antonio River Authority & National Pingtung University of Science and Technology.
Papers
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Journal Article
Tumorigenic Activity of the 4,5- and 9,10-Dihydrodiols of Benzo[j]fluoranthene and Their syn- and anti-Diol Epoxides in Newborn Mice
TL;DR: The most tumorigenic diol epoxide was anti-5-dihydroxy-6,6a-epoxy-4,5,6, 6a-tetrahydro-B[j]F, while the anti-diasteromers exhibited greater tumorsigenic activity.
Journal ArticleDOI
Synthesis of 2-methylbenzo[b]furans and 2-methylbenzo[b]thiophens
TL;DR: In this article, 2-Methylbenzo[b]furans and 2-methylbenzo [b]-thiophens were obtained from the corresponding chloroallyl phenyl ethers and phenyl sulphides, respectively.
Journal ArticleDOI
Aryl and Arylalkyl Substituted 3-Hydroxypyridin-2(1H)-ones: Synthesis and Evaluation as Inhibitors of Influenza A Endonuclease.
Hye Yeon Sagong,Joseph D. Bauman,Aitor Nogales,Luis Martinez-Sobrido,Eddy Arnold,Edmond J. LaVoie +5 more
TL;DR: The structure–activity relationships associated with various para‐substituted 5‐phenyl derivatives of 6‐(p‐fluorophenyl)‐3‐hydroxypyridin‐2(1H)‐ones and the effect of using naphthyl, benzyl, and naphTHylmethyl groups as alternatives to the p‐fluarophenyl substituent on their activity as endonuclease inhibitors are reported.
Patent
Topoisomerase-targeting agents
TL;DR: In this paper, the authors provide compounds of formula I or formula (II), wherein the bond represented by --- is a single bond or a double bond, and R 1-R5, X, and Y have any of the meanings defined in the specification and their pharmaceutically acceptable salts.
Patent
Bacterial efflux pump inhibitors
Edmond J. LaVoie,Ajit K. Parhi,Gifty A. Blankson,Liping Wang,Xiao Chen,Yongzheng Zhang,Malvika Kaul,Daniel S. Pilch +7 more
TL;DR: In this article, compounds of formula I: and salts thereof are discussed and compositions of compositions comprising compounds of I and methods using compounds of the same type are presented. But they do not specify the properties of the compounds.