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Edna A. Trujillo
Researcher at University of Wisconsin-Madison
Publications - 12
Citations - 713
Edna A. Trujillo is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Proteome & Mass spectrometry. The author has an hindex of 6, co-authored 10 publications receiving 329 citations.
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Journal ArticleDOI
Large-Scale Multi-omic Analysis of COVID-19 Severity.
Katherine A. Overmyer,Evgenia Shishkova,Ian J. Miller,Joseph Balnis,Matthew N. Bernstein,Trenton M. Peters-Clarke,Jesse G. Meyer,Qiuwen Quan,Laura K. Muehlbauer,Edna A. Trujillo,Yuchen He,Amit Chopra,Hau Chieng,Anupama Tiwari,Marc A. Judson,Brett Paulson,Dain R. Brademan,Yunyun Zhu,Lia R. Serrano,Vanessa Linke,Lisa A. Drake,Alejandro P. Adam,Bradford S Schwartz,Harold A. Singer,Scott Swanson,Deane F. Mosher,Ron Stewart,Joshua J. Coon,Ariel Jaitovich +28 more
TL;DR: A web-based tool (covid-omics.app) is presented enabling interactive exploration of the compendium and its utility through a machine learning approach for prediction of COVID-19 severity is illustrated.
Journal ArticleDOI
Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling
Jonathan A. Stefely,Jonathan A. Stefely,Nicholas W. Kwiecien,Elyse C. Freiberger,Alicia L. Richards,Adam Jochem,Matthew J. P. Rush,Arne Ulbrich,Kyle P. Robinson,Kyle P. Robinson,Paul D. Hutchins,Mike T. Veling,Mike T. Veling,Xiao Guo,Xiao Guo,Zachary A. Kemmerer,Zachary A. Kemmerer,Kyle J. Connors,Edna A. Trujillo,Jacob Sokol,Jacob Sokol,Harald Marx,Michael S. Westphall,Alexander S. Hebert,David J. Pagliarini,David J. Pagliarini,Joshua J. Coon +26 more
TL;DR: A multi-omic data analysis and visualization tool is presented that is used to find covariance networks that can predict molecular functions, correlations between profiles of related gene deletions, gene-specific perturbations that reflect protein functions, and a global respiration deficiency response.
Posted ContentDOI
Large-scale Multi-omic Analysis of COVID-19 Severity
Katherine A. Overmyer,Evgenia Shishkova,Ian J. Miller,Joseph Balnis,Matthew N. Bernstein,Trenton M. Peters-Clarke,Jesse G. Meyer,Qiuwen Quan,Laura K. Muehlbauer,Edna A. Trujillo,Yuchen He,Amit Chopra,Hau Chieng,Anupama Tiwari,Marc A. Judson,Brett Paulson,Dain R. Brademan,Yunyun Zhu,Lia R. Serrano,Vanessa Linke,Lisa A. Drake,Alejandro P. Adam,Bradford S Schwartz,Harold A. Singer,Scott Swanson,Deane F. Mosher,Ron Stewart,Joshua J. Coon,Ariel Jaitovich +28 more
TL;DR: A web-based tool (covid-omics.app) is presented enabling interactive exploration of the compendium and illustrating its utility through a comparative analysis with published data and a machine learning approach for prediction of COVID-19 severity.
Journal ArticleDOI
Metabolic Remodeling during Biofilm Development of Bacillus subtilis
Tippapha Pisithkul,Jeremy W. Schroeder,Edna A. Trujillo,Ponlkrit Yeesin,David M. Stevenson,Tai Chaiamarit,Joshua J. Coon,Joshua J. Coon,Jue D. Wang,Daniel Amador-Noguez +9 more
TL;DR: It is demonstrated that acetoin production via acetolactate synthase is essential for robust biofilm growth and has the dual role of conserving redox balance and maintaining extracellular pH.
Journal ArticleDOI
A large-scale genome-lipid association map guides lipid identification.
Vanessa Linke,Katherine A. Overmyer,Katherine A. Overmyer,Ian J. Miller,Dain R. Brademan,Paul D. Hutchins,Edna A. Trujillo,Thiru R. Reddy,Thiru R. Reddy,Jason D. Russell,Emily M. Cushing,Kathryn L. Schueler,Donald S. Stapleton,Mary E. Rabaglia,Mark P. Keller,Daniel M. Gatti,Gregory R. Keele,Duy Pham,Karl W. Broman,Gary A. Churchill,Alan D. Attie,Joshua J. Coon +21 more
TL;DR: To discover the genetics of lipid features obtained through high resolution LC-MS/MS, liver and plasma from 384 Diversity Outbred mice were analyzed, and 3,283 molecular features were analyzed and compiled into a public web-resource termed LipidGenie, which suggests acyl chain-specific functions for proteins of the ABHD family.