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Ariel Jaitovich
Researcher at Albany Medical College
Publications - 53
Citations - 1772
Ariel Jaitovich is an academic researcher from Albany Medical College. The author has contributed to research in topics: Skeletal muscle & Medicine. The author has an hindex of 16, co-authored 41 publications receiving 1085 citations. Previous affiliations of Ariel Jaitovich include University of Buenos Aires & Northwestern University.
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Journal ArticleDOI
Large-Scale Multi-omic Analysis of COVID-19 Severity.
Katherine A. Overmyer,Evgenia Shishkova,Ian J. Miller,Joseph Balnis,Matthew N. Bernstein,Trenton M. Peters-Clarke,Jesse G. Meyer,Qiuwen Quan,Laura K. Muehlbauer,Edna A. Trujillo,Yuchen He,Amit Chopra,Hau Chieng,Anupama Tiwari,Marc A. Judson,Brett Paulson,Dain R. Brademan,Yunyun Zhu,Lia R. Serrano,Vanessa Linke,Lisa A. Drake,Alejandro P. Adam,Bradford S Schwartz,Harold A. Singer,Scott Swanson,Deane F. Mosher,Ron Stewart,Joshua J. Coon,Ariel Jaitovich +28 more
TL;DR: A web-based tool (covid-omics.app) is presented enabling interactive exploration of the compendium and its utility through a machine learning approach for prediction of COVID-19 severity is illustrated.
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HO-1 is located in liver mitochondria and modulates mitochondrial heme content and metabolism
Daniela P. Converso,Camille Taillé,Maria Cecilia Carreras,Ariel Jaitovich,Juan José Poderoso,Jorge Boczkowski +5 more
TL;DR: It is surmised that mitochondrial HO‐1 has important biological roles in regulating mitochondrial heme protein turnover and in protecting against conditions such as hypoxia, neurodegenerative diseases, or sepsis, in which substantially increased mitochondrial NO and oxidant production have been implicated.
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Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease. What We Know and Can Do for Our Patients
Ariel Jaitovich,Esther Barreiro +1 more
TL;DR: A general overview of skeletal muscle dysfunction in COPD is offered to highlight its relevance and magnitude to expert practitioners and scientists as well as to the average clinician dealing with patients with chronic respiratory diseases.
Journal ArticleDOI
High CO2 Levels Cause Skeletal Muscle Atrophy via AMP-activated Kinase (AMPK), FoxO3a Protein, and Muscle-specific Ring Finger Protein 1 (MuRF1)
Ariel Jaitovich,Martín Angulo,Emilia Lecuona,Laura A. Dada,Lynn C. Welch,Yuan Cheng,Galina A. Gusarova,Ermelinda Ceco,Chang Liu,Masahiko Shigemura,Esther Barreiro,Cam Patterson,Gustavo A. Nader,Jacob I. Sznajder +13 more
TL;DR: Evidence is provided that high CO2 activates skeletal muscle atrophy via AMPKα2-FoxO3a-MuRF1, which is of biological and potentially clinical significance in patients with lung diseases and hypercapnia.
Journal ArticleDOI
Mitochondrial extracellular signal-regulated kinases 1/2 (ERK1/2) are modulated during brain development
Mariana Alonso,Mariana Melani,Daniela P. Converso,Ariel Jaitovich,Cristina Paz,M. Cecilia Carreras,Jorge H. Medina,Juan José Poderoso +7 more
TL;DR: The results suggest that developmental mitochondrial activation of ERK1/2 cascade contributes to its nuclear translocation effects, providing information about mitochondrial energetic and redox status to the proliferating/differentiating nuclear pathways.