E
Eduard E. de Lange
Researcher at University of Virginia
Publications - 96
Citations - 5441
Eduard E. de Lange is an academic researcher from University of Virginia. The author has contributed to research in topics: Hyperpolarized Helium 3 & Magnetic resonance imaging. The author has an hindex of 37, co-authored 95 publications receiving 5145 citations. Previous affiliations of Eduard E. de Lange include Baystate Medical Center & University of Virginia Health System.
Papers
More filters
Journal ArticleDOI
MRI of the lungs using hyperpolarized noble gases.
Harald E. Möller,X. Josette Chen,Brian Saam,Klaus D. Hagspiel,G. Allan Johnson,Talissa A. Altes,Eduard E. de Lange,Hans-Ulrich Kauczor +7 more
TL;DR: The physics underlying the optical pumping process, imaging strategies coping with the nonequilibrium polarization, and effects of the alveolar microstructure on relaxation and diffusion of the noble gases are outlined.
Journal ArticleDOI
MR imaging and spectroscopy using hyperpolarized 129Xe gas: preliminary human results.
John P. Mugler,Bastiaan Driehuys,James R. Brookeman,Gordon D. Cates,Stuart S. Berr,Robert G. Bryant,Thomas M. Daniel,Eduard E. de Lange,J. Hunter Downs,Christopher J. Erickson,William Happer,Denise P. Hinton,Neal F. Kassel,Therese Maier,C. Douglas Phillips,Brian Saam,Karen L. Sauer,Mark E. Wagshul +17 more
TL;DR: The results suggest the feasibility of dissolved‐phase imaging of both the chest and brain with a resolution similar to that obtained with the gas‐phase images.
Journal ArticleDOI
Hyperpolarized 3He MR lung ventilation imaging in asthmatics: Preliminary findings
Talissa A. Altes,Patrick L. Powers,Jack Knight-Scott,Gary P. Rakes,Thomas A.E. Platts-Mills,Eduard E. de Lange,Bennett A. Alford,John P. Mugler,James R. Brookeman +8 more
TL;DR: Hyperpolarized 3He lung imaging can detect the small, reversible ventilation defects that characterize asthma and offers a direct method of assessing asthmatics and their response to therapy.
Journal ArticleDOI
Imaging the lungs in asthmatic patients by using hyperpolarized helium-3 magnetic resonance: assessment of response to methacholine and exercise challenge.
Saba Samee,Talissa A. Altes,Patrick L. Powers,Eduard E. de Lange,Jack Knight-Scott,Gary P. Rakes,John P. Mugler,Jonathan M. Ciambotti,Bennet A. Alford,James R. Brookeman,Thomas A.E. Platts-Mills +10 more
TL;DR: HHe3 magnetic resonance provides a new technique for imaging the distribution of inhaled air in the lungs and is suitable for following responses to treatment of asthma and changes after methacholine or exercise challenge.
Journal ArticleDOI
Emphysema: Hyperpolarized Helium 3 Diffusion MR Imaging of the Lungs Compared with Spirometric Indexes—Initial Experience
Michael Salerno,Eduard E. de Lange,Talissa A. Altes,Jonathon D. Truwit,James R. Brookeman,John P. Mugler +5 more
TL;DR: Hyperpolarized (3)He diffusion MR imaging demonstrated potential for use in evaluating the global and regional severity of emphysema and whether apparent diffusion coefficients (ADCs) measured with MR imaging correlate with spirometric indexes.