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Edward T. Kipreos
Researcher at University of Georgia
Publications - 54
Citations - 4525
Edward T. Kipreos is an academic researcher from University of Georgia. The author has contributed to research in topics: Caenorhabditis elegans & Cell cycle. The author has an hindex of 27, co-authored 52 publications receiving 4172 citations. Previous affiliations of Edward T. Kipreos include Johns Hopkins University.
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Journal ArticleDOI
The F-box protein family.
Edward T. Kipreos,Michele Pagano +1 more
TL;DR: The F-box is a protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction that links the F- box protein to other components of the SCF complex by binding the core SCF component Skp I.
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cul-1 Is Required for Cell Cycle Exit in C. elegans and Identifies a Novel Gene Family
TL;DR: The mutant phenotype suggests that G1-to-S phase progression is accelerated, overriding mechanisms for mitotic arrest and producing abnormally small cells in C. elegans.
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MEC-17 is an α-tubulin acetyltransferase
Jyothi S. Akella,Dorota Wloga,Jihyun Kim,Natalia G. Starostina,Sally Lyons-Abbott,Naomi S. Morrissette,Scott T. Dougan,Edward T. Kipreos,Jacek Gaertig +8 more
TL;DR: It is shown that MEC-17, a protein related to the Gcn5 histone acetyltransferases and required for the function of touch receptor neurons in Caenorhabditis elegans, acts as a K40-specific acetyl transferase for α-tubulin.
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CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing.
TL;DR: It is proposed that CUL-4 prevents aberrant re-initiation of DNA replication, at least in part, by facilitating the degradation of CDT-1, which is required for DNA replication in Caenorhabditis elegans.
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Cullin-RING ubiquitin ligases: global regulation and activation cycles
Dimple R. Bosu,Edward T. Kipreos +1 more
TL;DR: This review focuses on the global regulation of CRL complexes, encompassing: neddylation, deneddylations by the COP9 Signalosome (CSN), inhibitory binding by CAND1, and the dimerization of C RL complexes.