J
Jacek Gaertig
Researcher at University of Georgia
Publications - 86
Citations - 7059
Jacek Gaertig is an academic researcher from University of Georgia. The author has contributed to research in topics: Tetrahymena & Microtubule. The author has an hindex of 37, co-authored 83 publications receiving 6364 citations. Previous affiliations of Jacek Gaertig include J. Craig Venter Institute & University of Rochester.
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Journal ArticleDOI
Microtubule acetylation promotes kinesin-1 binding and transport
Nathan A. Reed,Dawen Cai,T. Lynne Blasius,Gloria T. Jih,Edgar Meyhofer,Jacek Gaertig,Kristen J. Verhey +6 more
TL;DR: It is shown that the kinesin-1 cargo protein JNK-interacting protein 1 (JIP1) is localized to only a subset of neurites in cultured neuronal cells, and microtubule PTMs are important markers of distinct microtubules populations and that they act to control motor-protein trafficking.
Journal ArticleDOI
Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote
Jonathan A. Eisen,Robert S. Coyne,Martin Wu,Dongying Wu,Mathangi Thiagarajan,Jennifer R. Wortman,Jonathan H. Badger,Qinghu Ren,Paolo Amedeo,Kristie M. Jones,Luke J. Tallon,Arthur L. Delcher,Steven L. Salzberg,Joana C. Silva,Brian J. Haas,William H. Majoros,Maryam Farzad,Jane M. Carlton,Jane M. Carlton,Roger Smith,Jyoti Garg,Ronald E. Pearlman,Kathleen M Karrer,Lei Sun,Gerard Manning,Nels C. Elde,Aaron P. Turkewitz,David J. Asai,David E. Wilkes,Yufeng Wang,Hong-Hong Cai,Kathleen E Collins,B. Andrew Stewart,Suzanne R. Lee,Katarzyna Wilamowska,Zasha Weinberg,Walter L. Ruzzo,Dorota Wloga,Jacek Gaertig,Joseph Frankel,Che-Chia Tsao,Martin A. Gorovsky,Patrick J. Keeling,Ross F. Waller,Nicola J. Patron,J. Michael Cherry,Nicholas A. Stover,Cynthia J. Krieger,Christina del Toro,Hilary F. Ryder,Sondra Williamson,Rebecca A Barbeau,Eileen P. Hamilton,Eduardo Orias +53 more
TL;DR: The T. thermophila genome has been used for functional genomic studies to address biological, biomedical, and biotechnological questions of fundamental importance as mentioned in this paper, and it has been shown that the excision of DNA from the MIC to generate the macronucleus specifically targets foreign DNA as a form of genome self-defense.
Journal ArticleDOI
The tubulin code.
Kristen J. Verhey,Jacek Gaertig +1 more
TL;DR: Recent progress in understanding how the tubulin code is generated, maintained, and read by microtubule effectors is reviewed.
Journal ArticleDOI
MEC-17 is an α-tubulin acetyltransferase
Jyothi S. Akella,Dorota Wloga,Jihyun Kim,Natalia G. Starostina,Sally Lyons-Abbott,Naomi S. Morrissette,Scott T. Dougan,Edward T. Kipreos,Jacek Gaertig +8 more
TL;DR: It is shown that MEC-17, a protein related to the Gcn5 histone acetyltransferases and required for the function of touch receptor neurons in Caenorhabditis elegans, acts as a K40-specific acetyl transferase for α-tubulin.
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Tubulin Polyglutamylase Enzymes Are Members of the TTL Domain Protein Family
Carsten Janke,Krzysztof Rogowski,Dorota Wloga,Catherine Regnard,Andrey V. Kajava,Jean-Marc Strub,Nevzat Temurak,Juliette van Dijk,Dominique Boucher,Alain Van Dorsselaer,Swati Suryavanshi,Jacek Gaertig,Bernard Eddé +12 more
TL;DR: The neuronal tubulin polyglutamylase is a protein complex containing a tubulin tyrosine ligase–like protein, TTLL1, a member of a large family of proteins with a TTL homology domain, whose members could catalyze ligations of diverse amino acids to tubulins or other substrates.