E
Edward Zagha
Researcher at University of California, Riverside
Publications - 38
Citations - 2726
Edward Zagha is an academic researcher from University of California, Riverside. The author has contributed to research in topics: Sensory system & Motor cortex. The author has an hindex of 16, co-authored 31 publications receiving 2211 citations. Previous affiliations of Edward Zagha include Stanford University & New York University.
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Journal ArticleDOI
Waking State: Rapid Variations Modulate Neural and Behavioral Responses.
Matthew J. McGinley,Martin Vinck,Jacob Reimer,Renata Batista-Brito,Edward Zagha,Cathryn R. Cadwell,Andreas S. Tolias,Jessica A. Cardin,David A. McCormick +8 more
TL;DR: By taking fluctuations in state into account, neural response (co)variability is significantly reduced, revealing the brain to be more reliable and predictable than previously thought.
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The Largest Group of Superficial Neocortical GABAergic Interneurons Expresses Ionotropic Serotonin Receptors
TL;DR: Fast modulation of serotonergic and cholinergic transmission may influence cortical activity through an enhancement of GABAergic synaptic transmission from 5-HT3AR-expressing neurons during sensory process depending on different behavioral states.
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Motor cortex feedback influences sensory processing by modulating network state.
TL;DR: It is shown that primary motor and somatosensory cortices undergo coherent, context-dependent changes in network state, and the involvement of the direct corticocortical feedback pathway provides temporally precise and spatially targeted modulation of network dynamics.
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K+ Channels at the Axon Initial Segment Dampen Near-Threshold Excitability of Neocortical Fast-Spiking GABAergic Interneurons
TL;DR: It is shown that FS cells in layer 2/3 barrel cortex possess a dampening mechanism mediated by Kv1.1-containing potassium channels localized to the axon initial segment, which provides a key counterbalance to the established rapid-response characteristics of FS cells.
Journal ArticleDOI
DPP10 modulates Kv4-mediated A-type potassium channels
Edward Zagha,Andrés Ozaita,Su Ying Chang,Marcela S. Nadal,Udele Lin,Michael J. Saganich,Thomas J. McCormack,Karen O. Akinsanya,Shu Y. Qi,Bernardo Rudy +9 more
TL;DR: DPP10 is found to be prominently expressed in brain neuronal populations that also express Kv4 subunits and the experiments suggest that DPP10 contributes to the molecular composition of A-type currents in the central nervous system.