Eileen T. Dimalanta

TL;DR: It is found that lateral gene transfer is far more extensive than previously anticipated and 1,387 new genes encoded in strain-specific clusters of diverse sizes were found in O157:H7, including candidate virulence factors, alternative metabolic capacities, several prophages and other new functions—all of which could be targets for surveillance.

TL;DR: The approach was to use replica molding to construct silastic devices to consistently deposit oriented, elongated DNA molecules onto charged surfaces, creating massive single molecule arrays, which were analyzed for both physical and biochemical insights within an integrated environment that created large data sets.

TL;DR: An extended Brownian dynamics simulation method is used to characterize the dynamics of long DNA molecules flowing in microchannels, finding that the relaxation time increases due to confinement in agreement with scaling predictions.

TL;DR: This work has constructed NheI and XhoI optical maps of Escherichia coli O157:H7 solely from genomic DNA molecules to provide a uniquely valuable scaffold for contig closure and sequence validation.

TL;DR: The Malaria Genome Consortium was formed to sequence and annotate the entire 24.6-Mb genome of the unicellular parasite Plasmodium falciparum.