E
Eitan Shaulian
Researcher at Hebrew University of Jerusalem
Publications - 23
Citations - 10415
Eitan Shaulian is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Transcription factor & JUNB. The author has an hindex of 19, co-authored 22 publications receiving 9072 citations. Previous affiliations of Eitan Shaulian include Weizmann Institute of Science & University of California, San Diego.
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Journal ArticleDOI
Metalloprotease type III effectors that specifically cleave JNK and NF‐κB
Kobi Baruch,Lihi Gur-Arie,Chen Nadler,Simi Koby,Gal Yerushalmi,Yinon Ben-Neriah,Orli Yogev,Eitan Shaulian,C. Guttman,Raz Zarivach,Ilan Rosenshine +10 more
TL;DR: It is shown that NleC and NleD co‐operate and complement other EPEC effectors in accomplishing maximal inhibition of IL‐8 secretion, a remarkable example of a pathogen using multiple effectors to manipulate systematically the host inflammatory response signalling network.
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Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response.
TL;DR: Upon DNA damage, a cytosolic form of the mitochondrial enzyme fumarase moves into the nucleus where, by virtue of its enzymatic activity, it participates in the cell's response to DNA damage.
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AP-1: linking hydrogen peroxide and oxidative stress to the control of cell proliferation and death.
Michael Karin,Eitan Shaulian +1 more
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Induction of Mdm2 and enhancement of cell survival by bFGF
Eitan Shaulian,Eitan Shaulian,Dalia Resnitzky,Ohad Shifman,Giovanni Blandino,Abraham Amsterdam,Avner Yayon,Moshe Oren +7 more
TL;DR: It is reported here that exposure of fibroblasts to bFGF, which confers upon them increased survival, also causes at the same time an increase in cellular levels of the Mdm2 oncoprotein, suggesting that induction of MDM2 and the subsequent inhibition of p53 function may contribute, at least partially, to the anti-apoptotic effects of bF GF and possibly some other survival factors.
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MDM2 and Fbw7 cooperate to induce p63 protein degradation following DNA damage and cell differentiation
Francesco Galli,Mariangela Rossi,Yuri D'Alessandra,Marco De Simone,Teresa Lopardo,Ygal Haupt,Osnat Alsheich-Bartok,Shira Anzi,Eitan Shaulian,Viola Calabrò,Girolama La Mantia,Luisa Guerrini +11 more
TL;DR: The findings suggest that following DNA damage and cellular differentiation MDM2 and Fbw7 can cooperate to regulate the levels of the pro-proliferative ΔNp63α protein.