E
Eleanor J. Fraser
Researcher at University of California, San Francisco
Publications - 11
Citations - 911
Eleanor J. Fraser is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Rituximab & Primary central nervous system lymphoma. The author has an hindex of 9, co-authored 10 publications receiving 753 citations.
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Journal ArticleDOI
Estrogen Masculinizes Neural Pathways and Sex-Specific Behaviors
Melody V. Wu,Devanand S. Manoli,Eleanor J. Fraser,Jennifer K. Coats,Jessica Tollkuhn,Shin-ichiro Honda,Nobuhiro Harada,Nirao M. Shah +7 more
TL;DR: The results suggest that aromatization of testosterone into estrogen is important for the development and activation of neural circuits that control male territorial behaviors.
Journal ArticleDOI
The Androgen Receptor Governs the Execution, but Not Programming, of Male Sexual and Territorial Behaviors
Scott A. Juntti,Jessica Tollkuhn,Melody V. Wu,Eleanor J. Fraser,Taylor Soderborg,Stella Tan,Shin-ichiro Honda,Nobuhiro Harada,Nirao M. Shah +8 more
TL;DR: These findings indicate that testosterone acts as a precursor to estrogen to masculinize the brain and behavior, and signals via AR to control the levels of male behavioral displays.
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Phase 1 investigation of lenalidomide/rituximab plus outcomes of lenalidomide maintenance in relapsed CNS lymphoma
James L. Rubenstein,Huimin Geng,Eleanor J. Fraser,Paul Formaker,Lingjing Chen,Jigyasa Sharma,Phoebe Killea,Kaylee Choi,Jenny Ventura,John Kurhanewicz,Clifford A. Lowell,Jimmy Hwang,Patrick A. Treseler,Penny K. Sneed,Jing Li,Xiaomin Wang,Nianhang Chen,Jon A. Gangoiti,Pamela N. Munster,Bertil Damato +19 more
TL;DR: It is concluded that lenalidomide penetrates ventricular CSF and is active as monotherapy in relapsed CNS lymphomas and delays whole brain radiotherapy (WBRT) in patients with inadequate responses to lenalidumide.
Journal ArticleDOI
Females of an African cichlid fish display male-typical social dominance behavior and elevated androgens in the absence of males
TL;DR: In all-female communities of A. burtoni, some individuals acquire a male-typical dominance phenotype, including aggressive territorial defense, distinctive color patterns, and courtship behavior, and dominant females have higher levels of circulating androgens than either subordinate females or females in mixed-sex communities.
Journal ArticleDOI
Neural control of sexually dimorphic behaviors
TL;DR: A diverse array of novel sex differences in the nervous system, surprisingly modular control of various stereotyped dimorphic behavioral routines, and unanticipated sensory and central modulation of mating are reported.