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Elena Cerrada

Researcher at University of Zaragoza

Publications -  81
Citations -  2578

Elena Cerrada is an academic researcher from University of Zaragoza. The author has contributed to research in topics: Reactivity (chemistry) & Thioredoxin reductase. The author has an hindex of 25, co-authored 78 publications receiving 2084 citations. Previous affiliations of Elena Cerrada include Spanish National Research Council & Universidad Pública de Navarra.

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Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer

Inés Mármol, +4 more
- 19 Jan 2017 - 
TL;DR: The choice of first-line treatment in CRC follows a multimodal approach based on tumour-related characteristics and usually comprises surgical resection followed by chemotherapy combined with monoclonal antibodies or proteins against vascular endothelial growth factor (VEGF) and epidermal growth receptor (EGFR).
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Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity, and thioredoxin reductase inhibition of a series of gold(I) complexes containing hydrophilic phosphine ligands.

Elena Vergara, +8 more
- 04 Jan 2010 - 
TL;DR: The gold(I)–phosphine complexes efficiently inhibited cytosolic and mitochondrial TrxRs at concentrations that did not affect the related oxidoreductase glutathione reductase (GR).
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Antiproliferative Activity of Gold(I) Alkyne Complexes Containing Water-Soluble Phosphane Ligands

Elena Vergara, +5 more
- 11 May 2010 - 
TL;DR: A series of mono-, di-, and trinuclear organometallic alkynyl phosphane gold(I) complexes containing the stable and water-soluble PTA and DAPTA ligands have been synthesized and characterized as mentioned in this paper.
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Synthesis, Characterization, and in Vitro Cytotoxicity of Some Gold(I) and Trans Platinum(II) Thionate Complexes Containing Water-Soluble PTA and DAPTA Ligands. X-ray Crystal Structures of [Au(SC4H3N2)(PTA)], trans-[Pt(SC4H3N2)2(PTA)2], trans-[Pt(SC5H4N)2(PTA)2], and trans-[Pt(SC5H4N)2(DAPTA)2]

Susana Miranda, +6 more
- 30 Apr 2008 - 
TL;DR: A series of gold(I) and platinum(II) complexes of the type [Au(SR)(P)] and trans-[Pt(SR) 2(P) 2] demonstrated potent cytotoxicity for ovarian, colon, renal, and melanoma cancer cell lines on the basis of a comparison with ID 50 values for some established cytotoxic drugs.
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Organometallic gold(I) and gold(III) complexes containing 1,3,5-triaza-7-phosphaadamantane (TPA): Examples of water-soluble organometallic gold compounds

Fabian Mohr, +2 more
- 01 Jan 2006 - 
TL;DR: The organometallic gold(I) complexes [Au(C⋮CCRR‘OH)(TPA)] (R = R‘ = H, Me, Ph and R = Me, R' = Et) as well as the gold(III) complexes trans-[Au (C6F5)2(TPA)2]OTf and [Aus(C6 F5)3(TMA)] (TPA = 1,3,5-triaza-7phosphaadamantane) were prepared and fully