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Elena García-Ruiz
Researcher at University of Málaga
Publications - 8
Citations - 1024
Elena García-Ruiz is an academic researcher from University of Málaga. The author has contributed to research in topics: Liver disease & Survival analysis. The author has an hindex of 4, co-authored 7 publications receiving 960 citations.
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Journal ArticleDOI
Drug-Induced Liver Injury: An Analysis of 461 Incidences Submitted to the Spanish Registry Over a 10-Year Period
Raúl J. Andrade,M. Isabel Lucena,M. Carmen Fernández,G. Pelaez,Ketevan Pachkoria,Elena García-Ruiz,B. García-Muñoz,Rocío González-Grande,Angeles Pizarro,José Antonio Durán,Manuel Jimenez,Luis Rodrigo,Manuel Romero-Gómez,J.M. Navarro,Ramon Planas,Joan Costa,Africa Borras,Aina Soler,Javier Salmerón,Rafael Martín-Vivaldi +19 more
TL;DR: Patients with drug-induced hepatocellular jaundice have 11.7% chance of progressing to death or transplantation, and amoxicillin-clavulanate stands out as the most common drug related to DILI.
Journal ArticleDOI
HLA class II genotype influences the type of liver injury in drug-induced idiosyncratic liver disease.
Raúl J. Andrade,M. Isabel Lucena,Anabel Alonso,Miren García-Cortés,Elena García-Ruiz,Rafael Benitez,M. Carmen Fernández,G. Pelaez,Manuel L. Romero,Raquel Corpas,José Antonio Durán,Manuel Jimenez,Luis Rodrigo,F. Nogueras,Rafael Martín-Vivaldi,J.M. Navarro,Javier Salmerón,Felipe Sánchez de la Cuesta,Ramón Hidalgo +18 more
TL;DR: There is no association between any specific HLA allele and the propensity to develop DIILD, however, the genetic influence associated with HLA class II alleles appears to play a role in the biochemical expression of liver injury in cholestatic/mixed hepatotoxicity and may explain why a given drug may cause different patterns of liver damage.
Journal Article
Flutamide-induced hepatotoxicity: report of a case series.
García Cortés M,R.J. Andrade,M.I. Lucena,Sánchez Martínez H,M.C. Fernandez,Ferrer T,Rafael Martín-Vivaldi,G. Pelaez,Suárez F,Manuel Romero-Gómez,Montero Jl,E. Fraga,R. Camargo,Alcántara R,Pizarro Ma,Elena García-Ruiz,Rosemary-Gómez M +16 more
TL;DR: Flutamide can induce severe acute hepatitis, probably due to an idiosyncratic metabolic mechanism, and Liver tests monitoring should probably be mandatory during the first months of flutamide therapy and the drug withdrawn if transaminases began to increase.
Journal ArticleDOI
Chronic hepatitis C, ibuprofen, and liver damage.
Raúl J. Andrade,María Isabel Lucena,Miren García-Cortés,Elena García-Ruiz,Eva Fernández-Bonilla,Luis Vázquez +5 more
TL;DR: Results of liver tests became normal during the subsequent 2 months and the histological picture was consistent with drug-induced hepatic injury, the first published report of liver injury due to moxifloxacin.