S
Sandra Fischer
Researcher at University Health Network
Publications - 114
Citations - 6767
Sandra Fischer is an academic researcher from University Health Network. The author has contributed to research in topics: Medicine & Liver transplantation. The author has an hindex of 28, co-authored 95 publications receiving 4987 citations. Previous affiliations of Sandra Fischer include Mount Sinai Hospital, Toronto & University of Toronto.
Papers
More filters
Journal ArticleDOI
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer
Hervé Tiriac,Pascal Belleau,Dannielle D. Engle,Dennis Plenker,Astrid Deschênes,Tim D.D. Somerville,Fieke E. M. Froeling,Richard A. Burkhart,Robert E. Denroche,Gun-Ho Jang,Koji Miyabayashi,C. Megan Young,C. Megan Young,Hardik Patel,Michelle Ma,Joseph F. LaComb,Randze Lerie Palmaira,Ammar A. Javed,Jasmine Huynh,Molly E. Johnson,Kanika Arora,Nicolas Robine,Minita Shah,Rashesh Sanghvi,Austin Goetz,Cinthya Y. Lowder,Laura A. Martello,Else Driehuis,Nicolas Lecomte,Gokce Askan,Christine A. Iacobuzio-Donahue,Hans Clevers,Laura D. Wood,Ralph H. Hruban,Elizabeth D. Thompson,Andrew J. Aguirre,Brian M. Wolpin,Aaron R. Sasson,Joseph Kim,Maoxin Wu,Juan Carlos Bucobo,Peter J. Allen,Divyesh V. Sejpal,William Nealon,James Sullivan,Jordan M. Winter,Phyllis A. Gimotty,Jean L. Grem,Dominick J. DiMaio,Jonathan M. Buscaglia,Paul M. Grandgenett,Jonathan R. Brody,Michael A. Hollingsworth,Grainne M. O'Kane,Faiyaz Notta,Edward J. Kim,James M. Crawford,Craig Devoe,Allyson J. Ocean,Christopher L. Wolfgang,Kenneth H. Yu,Ellen Li,Christopher R. Vakoc,Benjamin Hubert,Sandra Fischer,Sandra Fischer,Julie M. Wilson,Richard A. Moffitt,Jennifer J. Knox,Alexander Krasnitz,Steven Gallinger,Steven Gallinger,Steven Gallinger,David A. Tuveson +73 more
TL;DR: A pancreatic cancer patient-derived organoid (PDO) library is generated that recapitulates the mutational spectrum and transcriptional subtypes of primary Pancreatic cancer and proposes that combined molecular and therapeutic profiling of PDOs may predict clinical response and enable prospective therapeutic selection.
Journal ArticleDOI
Intestinal Microbiota in Patients With Nonalcoholic Fatty Liver Disease
Marialena Mouzaki,Elena M. Comelli,Bianca M. Arendt,Julia Bonengel,Scott Fung,Scott Fung,Sandra Fischer,Sandra Fischer,Ian D. McGilvray,Ian D. McGilvray,Johane P. Allard,Johane P. Allard +11 more
TL;DR: There continued to be a significant association between the presence of NASH and lower percentage Bacteroidetes even after adjusting for these variables and body mass index and dietary fat intake.
Journal Article
Intestinal Microbiota in Patients with Non-Alcoholic Fatty Liver Disease
Marialena Mouzaki,Elena M. Comelli,Bianca M. Arendt,Julia Bonengel,Scott Fung,Sandra Fischer,Ian D. McGilvray,Johane P. Allard +7 more
TL;DR: In this article, a prospective, cross-sectional study was aimed at identifying differences in the intestinal microbiota (IM) composition of patients with non-alcoholic fatty liver disease (NAFLD) and living liver donors as healthy controls (HC).
Journal ArticleDOI
Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial
Kyaw L. Aung,Sandra Fischer,Sandra Fischer,Robert E. Denroche,Gun-Ho Jang,Anna Dodd,Sean Creighton,Bernadette Southwood,Sheng-Ben Liang,Dianne Chadwick,Amy Zhang,Grainne M. O'Kane,Hamzeh Albaba,Shari Moura,Robert C. Grant,Jessica Miller,Faridah Mbabaali,Danielle Pasternack,Ilinca Lungu,John M. S. Bartlett,Sangeet Ghai,Mathieu Lemire,Spring Holter,Ashton A. Connor,Richard A. Moffitt,Richard A. Moffitt,Jen Jen Yeh,Lee Timms,Paul M. Krzyzanowski,Neesha C. Dhani,David W. Hedley,Faiyaz Notta,Julie M. Wilson,Malcolm J. Moore,Steven Gallinger,Jennifer J. Knox +35 more
TL;DR: Prospective genomic profiling of advanced PDAC is feasible, and early data indicate that chemotherapy response differs among patients with different genomic/transcriptomic subtypes.
Journal ArticleDOI
Handheld Computing in Medicine
TL;DR: The authors concluded that only a small number of articles provide evidence-based information about the use of PDAs in medicine and that the majority of articles provided descriptive information, which is nevertheless of value.