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Eleonora Grippa

Researcher at Sapienza University of Rome

Publications -  22
Citations -  444

Eleonora Grippa is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Albumin & Serum albumin. The author has an hindex of 11, co-authored 22 publications receiving 403 citations.

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Antimicrobial and anti-lipase activity of quercetin and its C2-C16 3-O-acyl-esters.

TL;DR: 3-O-acyl-quercetines, being more active and more lipophilic, could be more effective than Q when applied to the skin or mucosae, and deserve to be studied further.
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Simultaneous determination of hydrocortisone, dexamethasone, indomethacin, phenylbutazone and oxyphenbutazone in equine serum by high-performance liquid chromatography.

TL;DR: Ethyl acetate extracts of equine serum, containing 0-5 microg/ml of hydrocortisone (HYD), dexamethasone (DEX), oxyphenbutazone (OPB), indomethacin (IND), phenylbutaz one (PB) and probenecid as internal standard, appeared appropriate for anti-doping control of racehorses.
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Inhibition of heat-induced denaturation of albumin by nonsteroidal antiinflammatory drugs (NSAIDs): Pharmacological implications

TL;DR: A survey of nonsteroidal antiinflammatory drugs in rheumatoid arthritis found that NSAIDs were slightly less active than FA and that the HPLC method was capable of distinguishing true antiaggregant agents like FA and NSAIDs from substances capable of inhibiting the precipitation of denatured protein aggregates.
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Inhibition of protein denaturation by fatty acids, bile salts and other natural substances: a new hypothesis for the mechanism of action of fish oil in rheumatic diseases.

TL;DR: It is speculated that the antidenaturant activity of fish oil may be partly (in addition to the known effect on endogenous eicosanoid composition) responsible for its beneficial effects in rheumatoid arthritis and other rheumatic conditions.
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Inhibition of Candida rugosa lipase by berberine and structurally related alkaloids, evaluated by high-performance liquid chromatography.

TL;DR: Berberine and a number of structurally related alkaloids such as chelidonine, chelerythrine, and sanguinarine appeared active and were of interest because they are used in pathological conditions in which microbial lipases could play a pathogenic role.