Journal ArticleDOI
Antimicrobial and anti-lipase activity of quercetin and its C2-C16 3-O-acyl-esters.
Maria Teresa Gatto,Serena Falcocchio,Eleonora Grippa,Gabriela Mazzanti,Lucia Battinelli,Giovanni Nicolosi,Daniela Lambusta,Luciano Saso +7 more
TLDR
3-O-acyl-quercetines, being more active and more lipophilic, could be more effective than Q when applied to the skin or mucosae, and deserve to be studied further.About:
This article is published in Bioorganic & Medicinal Chemistry.The article was published on 2002-02-01. It has received 94 citations till now. The article focuses on the topics: Candida glabrata & Shigella flexneri.read more
Citations
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Journal ArticleDOI
Comprehensive review of antimicrobial activities of plant flavonoids
TL;DR: The development and application of flavonoid-based drugs could be a promising approach for antibiotic-resistant infections and improve understanding of the biological and molecular roles of plant flavonoids, focusing mostly on their antimicrobial activities.
Journal ArticleDOI
Quercetin: potentials in the prevention and therapy of disease.
TL;DR: The current review presents the most recent findings on quercetin with regard to the pharmacology, the in-vitro and in- vivo effects in different cell systems and animal models, and the clinical effects in humans, finding that quercets enhances physical power by yet unclear mechanisms.
Journal ArticleDOI
Suppression of bacterial cell–cell signalling, biofilm formation and type III secretion system by citrus flavonoids
Amit Vikram,Guddadarangavvanahally K. Jayaprakasha,Palmy R. Jesudhasan,Suresh D. Pillai,Bhimanagouda S. Patil +4 more
TL;DR: This study investigated the quorum sensing, biofilm and type three secretion system (TTSS) inhibitory properties of citrus flavonoids to find out if they have an inhibitory effect on fruit flavonoid-like properties.
Journal ArticleDOI
Multifactorial aspects of antimicrobial activity of propolis.
TL;DR: Adding EEP to antibacterial tested drugs, it drastically increased the antimicrobial effect of ampicillin, gentamycin and streptomycin, moderately the one of chloramphenicol, ceftriaxon and vancomycin, while there was no effect with erithromycin.
Journal ArticleDOI
Flavonoid interactions during digestion, absorption, distribution and metabolism: a sequential structure-activity/property relationship-based approach in the study of bioavailability and bioactivity
Gerard Bryan Gonzales,Guy Smagghe,Charlotte Grootaert,Moisés João Zotti,Katleen Raes,John Van Camp +5 more
TL;DR: This approach reveals specific bioactive properties of flavonoids in the gastrointestinal tract as well as various barriers for their bioavailability, and determines the effect of different structural characteristics on the overall bioavailability of Flavonoids.
References
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Journal ArticleDOI
Review of the biology of quercetin and related bioflavonoids
J.V. Formica,W. Regelson +1 more
TL;DR: The role of flavonoids may transcend their presence in food as mentioned in this paper, however, the amount of quercetin that remains biologically available may not be of sufficient concentration, theoretically, to explain the beneficial effects seen with the Mediterranean diet.
Book
Manual of Pharmacologic Calculations: With Computer Programs
TL;DR: A manual of Pharmacologic Calculations with Computer Programs with Computer programs, published in 1981, provides an introduction to the science of pharmacologic calculation and its applications in medicine.
Journal ArticleDOI
Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds
Jussi-Pekka Rauha,Susanna Remes,Marina Heinonen,Anu Hopia,Marja P Kähkönen,Tytti S. Kujala,Kalevi Pihlaja,Heikki Vuorela,Pia Vuorela +8 more
TL;DR: Flavone, quercetin and naringenin were effective in inhibiting the growth of the organisms and purple loosestrife was the most active plant extracts against gram-positive Staphylococcus aureus.
Journal ArticleDOI
Antiviral effect of flavonoids on human viruses.
TL;DR: The effect of several naturally occurring dietary flavonoids including quercetin, naringin, hesperetin, and catechin on the infectivity and replication of herpes simplex virus type 1 (HSV-1), polio-virus type 1, parainfluenza virus type 3 (Pf-3), and respiratory syncytial virus (RSV) was studied in vitro in cell culture monolayers employing the technique of viral plaque reduction as discussed by the authors.
Journal ArticleDOI
On the mechanism of antithrombotic action of flavonoids.
TL;DR: Flavonols are anti-thrombotic because they are selectively bound to mural platelet thrombi and owing to their free radical scavenging properties resuscitate biosynthesis and action of endothelial prostacyclin and EDRF.