E
Elias Castanas
Researcher at University of Crete
Publications - 211
Citations - 10660
Elias Castanas is an academic researcher from University of Crete. The author has contributed to research in topics: Receptor & Cancer. The author has an hindex of 45, co-authored 206 publications receiving 9367 citations. Previous affiliations of Elias Castanas include Pierre-and-Marie-Curie University & National and Kapodistrian University of Athens.
Papers
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Journal ArticleDOI
Recognition motifs for importin 4 [(L)PPRS(G/P)P] and importin 5 [KP(K/Y)LV] binding, identified by bio-informatic simulation and experimental in vitro validation
Athanasios A. Panagiotopoulos,Konstantina Kalyvianaki,Paraskevi K. Tsodoulou,Maria N. Darivianaki,Dimitris Dellis,George Notas,Vangelis Daskalakis,Panayiotis A. Theodoropoulos,Christos A. Panagiotidis,Elias Castanas,Marilena Kampa +10 more
TL;DR: In this article , the NLS signals for Importins 4 and 5 were identified through an unsupervised in silico approach, followed by experimental in vitro validation, and the sequences LPPRS(G/P)P and KP(K/Y)LV were identified and are proposed as recognition motifs for Importin4 and 5 binding, respectively.
Patent
Anti-cancer compounds
Elias Castanas,Marilena Kampa,Vasiliki Pelekanou,Joseph Vercauteren,Katerina Theodoropoulou,Fani Mavromati +5 more
TL;DR: In this paper, lipoylated proanthocyanidin compounds and their use in treating, preventing or ameliorating a disorder or disease influenced by the action of a membrane androgen receptor, including cancers are discussed.
Patent
Er-alpha-17p peptide, effects on stem cell differentiation
Dominique Gallo,Hichame Id Boufker,Guy Leclercq,Elias Castanas,Marilena Kampa,Vasiliki Pelekanou +5 more
TL;DR: In this paper, a peptide that stimulates mesenchymal stem cell differentiation into other cell types such as chondrocytes, myocytes, osteoblasts, pancreatic beta cells, adipocytes and neurocytes and methods using said peptide.
Patent
Treatment and prevention of inflammation
Abstract: Disclosed is method of treating or preventing an inflammatory condition, comprising administering to a person in need thereof an amount of a product derived from the plant Pistachia lentiscus var. chia effective to treat or prevent the inflammatory condition. In a preferred aspect the product is a dilution of the oily steam distillate of the resin. Also disclosed is a pharmaceutical composition comprising the product derived from the plant Pistachia lentiscus var. chia in a dilution of 10 −5 or less.
Journal ArticleDOI
Corrigendum to "Recognition motifs for importin 4 [(L)PPRS(G/P)P] and importin 5 [KP(K/Y)LV] binding, identified by bio-informatic simulation and experimental in vitro validation" [Comput Struct Biotechnol J 20 (2022) 5952-5961].
Athanasios A. Panagiotopoulos,Konstantina Kalyvianaki,Paraskevi K. Tsodoulou,Maria N. Darivianaki,Dimitris Dellis,George Notas,Vangelis Daskalakis,Panayiotis A. Theodoropoulos,Christos A. Panagiotidis,Elias Castanas,Marilena Kampa +10 more
TL;DR: In this paper , the authors correct the article DOI: 10.1016/j.csbj.2022.015 and 10.10.015, and present a new version of the article.