E
Elias Castanas
Researcher at University of Crete
Publications - 211
Citations - 10660
Elias Castanas is an academic researcher from University of Crete. The author has contributed to research in topics: Receptor & Cancer. The author has an hindex of 45, co-authored 206 publications receiving 9367 citations. Previous affiliations of Elias Castanas include Pierre-and-Marie-Curie University & National and Kapodistrian University of Athens.
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Journal ArticleDOI
A new automated method for the determination of the Total Antioxidant Capacity (TAC) of human plasma, based on the crocin bleaching assay
Marilena Kampa,Anastasia Nistikaki,Vassilios Tsaousis,Niki Maliaraki,George Notas,Elias Castanas +5 more
TL;DR: An automated assay to calculate the antioxidant capacity of plasma after a subtraction of all interference deriving from endogenous and/or exogenous metabolites is presented, which can be used as a useful indicator of the antioxidant value of foods and beverages in the daily diet.
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Estrogen anti-inflammatory activity on human monocytes is mediated through cross-talk between estrogen receptor ERα36 and GPR30/GPER1
Vasiliki Pelekanou,Marilena Kampa,Foteini Kiagiadaki,Alexandra Deli,Panayiotis P. Theodoropoulos,George Agrogiannis,Efstratios Patsouris,Andreas Tsapis,Elias Castanas,George Notas +9 more
TL;DR: The expression of estrogen receptors is assessed and it is reported that the only estrogen receptors expressed are estrogen receptor‐α 36‐kDa splice variant and G‐protein coupled receptor 30/G‐protein estrogen receptor 1, in a sex‐independent manner.
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Membrane androgen receptor activation induces apoptotic regression of human prostate cancer cells in vitro and in vivo.
Anastassia Hatzoglou,Marilena Kampa,Christina Kogia,Ioannis Charalampopoulos,Panayiotis A. Theodoropoulos,Ploutarchos Anezinis,Constantina Dambaki,Evangelia A. Papakonstanti,Efstathios N. Stathopoulos,Christos Stournaras,Achille Gravanis,Elias Castanas +11 more
TL;DR: Evidence is provided that activation of mAR by nonpermeable, BSA-coupled testosterone results in inhibition of L NCaP cell growth and induction in LNCaP cells of both apoptosis and the proapoptotic Fas protein, suggesting that activators of m AR may represent a new class of antitumoral agents of prostate cancer.
Journal ArticleDOI
Decreased Total and Corrected Antioxidant Capacity in Patients with Inflammatory Bowel Disease
Ioannis E. Koutroubakis,Niki Malliaraki,Philippos Dimoulios,Konstantinos Karmiris,Elias Castanas,Elias A. Kouroumalis +5 more
TL;DR: TAC and cTAC are significantly reduced in IBD patients compared with controls irrespective of disease activity, suggesting decreased antioxidant defenses may be a primary phenomenon severely compromising the mucosa and therefore increase susceptibility to oxidative tissue damage.
Journal ArticleDOI
Opioid alkaloids and casomorphin peptides decrease the proliferation of prostatic cancer cell lines (LNCaP, PC3 and DU145) through a partial interaction with opioid receptors
M. Kampa,Efstathia Bakogeorgou,Anastassia Hatzoglou,Anastassia Hatzoglou,Athina Damianaki,Pierre-Marie Martin,Elias Castanas,Elias Castanas +7 more
TL;DR: Findings indicate a putative role of opioids in prostate cancer cell growth.