Elias Castanas

TL;DR: A specific example of the use of a combination of the essential oils of these plants as an effective anti-viral product is presented and the experience gained in a case of a plant-based pharmaceutical development, by presenting the major steps and the continuum of the translational chain.

TL;DR: Neuronal differentiation of chromaffin cells results in a significant attenuation of these effects, via suppression of the expression of membrane androgen receptors suggesting, that the latter are specific for epithelioid chromAffin cells.

TL;DR: The findings for the surgical specimens and the cell line combined with previously published pharmacological data obtained from KAT45 cells suggest that kappa sites appear to be the most prevalent opioid binding sites in pheochromocytomas, which is in contrast to normal bovine adrenals, which contains mainly delta sites and few kappa-opioid binding sites.

TL;DR: It is suggested that the direct biuret method (whenever protein concentrations permit it) or the method of Lowry after solubilization of membranes with Triton X-100 (3–5%) should be used preferentially for the determination of membrane protein samples.

TL;DR: A method for computing similarities between empirical, statistical distributions of high-dimensional, low-sample datasets is developed and applied to hundreds of public -omics datasets stemming from different studies, creating a network of diseases whose statistical molecular patterns are similar.