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Elisabetta Profumo
Researcher at Istituto Superiore di Sanità
Publications - 92
Citations - 3458
Elisabetta Profumo is an academic researcher from Istituto Superiore di Sanità. The author has contributed to research in topics: Antigen & Echinococcus granulosus. The author has an hindex of 32, co-authored 79 publications receiving 2620 citations.
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Journal ArticleDOI
An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation
TL;DR: The relationship between Nrf2 signaling and the inflammation as well as possible approaches for the therapeutic modulation of this pathway are examined.
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Modulation of Human Immune Response by Echinococcus granulosus Antigen B and Its Possible Role in Evading Host Defenses
Rachele Riganò,Elisabetta Profumo,Fabrizio Bruschi,Giovanni Carulli,Antonio Azzara,S. Ioppolo,Brigitta Buttari,Elena Ortona,Paola Margutti,Antonella Teggi,Alessandra Siracusano +10 more
TL;DR: Findings confirm that AgB plays a role in the escape from early immunity by inhibiting PMN chemotaxis and add new information on the host-parasite relationship, suggesting thatAgB exploits the activation of T helper cells by eliciting a nonprotective Th2 cell response.
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Echinococcus granulosus antigen B impairs human dendritic cell differentiation and polarizes immature dendritic cell maturation towards a Th2 cell response.
Rachele Riganò,Brigitta Buttari,Elisabetta Profumo,Elena Ortona,Federica Delunardo,Paola Margutti,Vincenzo Mattei,Antonella Teggi,Maurizio Sorice,Alessandra Siracusano +9 more
TL;DR: Results suggest that E. granulosus escapes host immunosurveillance in two ways: by interfering with monocyte differentiation and by modulating DC maturation.
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Immunological markers indicating the effectiveness of pharmacological treatment in human hydatid disease
Rachele Riganò,Elisabetta Profumo,S. Ioppolo,S. Notargiacomo,Elena Ortona,Antonella Teggi,Alessandra Siracusano +6 more
TL;DR: In this paper, the authors evaluated the effectiveness of pharmacological treatment in human hydatid disease (Echinococcus granulosus infection) by using immunoblotting and ELISA.
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Native and recombinant antigens in the immunodiagnosis of human cystic echinococcosis
Elena Ortona,Rachele Riganò,Paola Margutti,Sergio Notargiacomo,S. Ioppolo,Sergio Vaccari,Stefano Barca,Brigitta Buttari,Elisabetta Profumo,Antonella Teggi,Alessandra Siracusano +10 more
TL;DR: The findings underline the need to standardize techniques and antigenic preparations and to improve the performance of immunodiagnosis by characterizing new antigens and detecting distinct immunoglobulin classes.