E
Elizabeth A. Mauldin
Researcher at University of Pennsylvania
Publications - 87
Citations - 2768
Elizabeth A. Mauldin is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 24, co-authored 80 publications receiving 2275 citations. Previous affiliations of Elizabeth A. Mauldin include Cornell University & University of Wisconsin-Madison.
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Journal ArticleDOI
Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling
Naomi H. Philip,Christopher P. Dillon,Annelise G. Snyder,Patrick Fitzgerald,Meghan A. Wynosky-Dolfi,Erin E. Zwack,Baofeng Hu,Louise FitzGerald,Elizabeth A. Mauldin,Alan M. Copenhaver,Sunny Shin,Lei Wei,Matthew W. Parker,Jinghui Zhang,Andrew Oberst,Douglas R. Green,Igor E. Brodsky +16 more
TL;DR: It is found that caspase-8, RIPK1, and FADD are required for YopJ-induced cell death and show that mice lacking caspases are severely susceptible to Yersinia infection and have defective proinflammatory cytokine production.
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Diminished Type III Collagen Promotes Myofibroblast Differentiation and Increases Scar Deposition in Cutaneous Wound Healing
TL;DR: The effect of Col3 expression on myofibroblast differentiation and scar formation in this model suggests a previously undefined role for this ECM protein in tissue regeneration and repair.
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Intracisternal cyclodextrin prevents cerebellar dysfunction and Purkinje cell death in feline Niemann-Pick type C1 disease
Charles H. Vite,Jessica H. Bagel,Gary P. Swain,Maria Prociuk,Tracey Sikora,Veronika M. Stein,Patricia O'Donnell,Therese Ruane,Sarah Ward,Alexandra Crooks,Su Li,Elizabeth A. Mauldin,Susan Stellar,Marc De Meulder,Mark L. Kao,Daniel S. Ory,Cristin Davidson,Marie T. Vanier,Steven U. Walkley +18 more
TL;DR: These studies in a feline animal model have provided critical data on efficacy and safety of drug administration directly into the central nervous system that will be important for advancing HPβCD into clinical trials.
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Prednisone and Vinblastine Chemotherapy for Canine Mast Cell Tumor—41 Cases (1992–1997)
TL;DR: Forty-one dogs with mast cell tumors were treated with oral prednisone and injectable vinblastine, both in the adjuvant setting and in dogs with gross disease, with apparent improvement over historical survival data employing surgery alone.
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Longitudinal Evaluation of the Skin Microbiome and Association with Microenvironment and Treatment in Canine Atopic Dermatitis
Charles W. Bradley,Daniel O. Morris,Shelley C. Rankin,Christine L. Cain,Ana M. Misic,Timothy Houser,Elizabeth A. Mauldin,Elizabeth A. Grice +7 more
TL;DR: Insight is provided into the relationship between the cutaneous microbiome and skin barrier function in atopic dermatitis, the impact of antimicrobial therapy on the skin microbiome is shown, and the utility of canine atopy dermatitis as a spontaneous nonrodent model is highlighted.