E
Elizabeth E. Powell
Researcher at Princess Alexandra Hospital
Publications - 195
Citations - 14979
Elizabeth E. Powell is an academic researcher from Princess Alexandra Hospital. The author has contributed to research in topics: Fibrosis & Fatty liver. The author has an hindex of 49, co-authored 189 publications receiving 13170 citations. Previous affiliations of Elizabeth E. Powell include Wellcome Trust Centre for Human Genetics & University of Queensland.
Papers
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Journal ArticleDOI
IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy
Vijayaprakash Suppiah,Max Moldovan,Golo Ahlenstiel,Thomas Berg,Martin Weltman,Maria Lorena Abate,Margaret F. Bassendine,Ulrich Spengler,Gregory J. Dore,Gregory J. Dore,Elizabeth E. Powell,Elizabeth E. Powell,Stephen M. Riordan,David Sheridan,Antonina Smedile,Vincenzo Fragomeli,Tobias Müller,Melanie Bahlo,Graeme J. Stewart,David R. Booth,Jacob George +20 more
TL;DR: The data suggest that host genetics may be useful for the prediction of drug response, and they also support the investigation of the role of IL28B in the treatment of HCV and in other diseases treated with IFN-α.
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The natural history of nonalcoholic steatohepatitis: A follow‐up study of forty‐two patients for up to 21 years
Elizabeth E. Powell,W. Graham E. Cooksley,Reginald Hanson,Jeffrey Searle,June W. Halliday,W. Powell +5 more
TL;DR: In individual patients, poorly controlled diabetes and rapid weight loss preceded the onset of steatohepatitis, and in the patients with extensive fibrosis the the liver disease evolved from one of active inflammation to one of inactive cirrhosis without fat or inflammation.
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Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus
Simon T. Bennett,Anneke Lucassen,S C Gough,Elizabeth E. Powell,Dag E. Undlien,L E Pritchard,Marilyn E. Merriman,Y Kawaguchi,M J Dronsfield,M J Dronsfield,Flemming Pociot +10 more
TL;DR: Although it is shown that the insulin gene is expressed biallelically in the adult pancreas, it is presented preliminary evidence that the level of transcription in vivo is correlated with allelic variation within the VNTR.
Journal ArticleDOI
Non-alcoholic fatty liver disease
TL;DR: In this paper, a global prevalence of 25% and is a leading cause of cirrhosis and hepatocellular carcinoma, and the leading causes of death in people with NAFLD are cardiovascular disease and extrahepatic malignancy.
Journal ArticleDOI
Relationship Between Steatosis, Inflammation, and Fibrosis in Chronic Hepatitis C: A Meta-Analysis of Individual Patient Data
Gioacchino Leandro,Alessandra Mangia,Jason M. Hui,Paolo Fabris,Laura Rubbia Brandt,Guido Colloredo,Luigi Elio Adinolfi,Tarik Asselah,Julie R. Jonsson,Antonina Smedile,Norah A. Terrault,Valerio Pazienza,Maria Teresa Giordani,Emiliano Giostra,Aurelio Sonzogni,Giuseppe Ruggiero,Patrick Marcellin,Elizabeth E. Powell,Jacob George,Francesco Negro +19 more
TL;DR: In this large and geographically different group of CHC patients, steatosis is confirmed as significantly and independently associated with fibrosis in CHC.