Ellen M. Olzomer

TL;DR: Together, these data provide a mechanism as to how TIH, prevalent in people with impaired glucose metabolism, contributes to cardiovascular disease and may suggest that strategies aimed at targeting the S100A8/A9-RAGE (receptor for advanced glycation end products) axis could represent a viable approach to protect the vulnerable blood vessels in diabetes mellitus.

TL;DR: It is shown that lipogenesis is dispensable for liver tumorigenesis in mice treated with DEN, and an important role for ACC enzymes in redox regulation and cell survival is identified.

TL;DR: Evidence in mice is shown that the mitochondrial uncoupler BAM15 effectively induces fat loss without affecting food intake or compromising lean body mass.

TL;DR: The circular transcriptome specific for EC as determined by RNA sequencing found that the overall abundance of circRNAs is lower in EC than in normal endometrium and there are numerous ‘hotspot’ genes from whichcircRNAs are transcribed that may account for alterations in circRNA expression between the normal and malignantendometrium.

TL;DR: Four lincRNAs, characterised in this study, represent high priority genes to be tested for functional significance in the pathogenesis and/or progression of endometrial cancer and have potential to be released into the bloodstream.