E
Emilio A. Emini
Researcher at Pfizer
Publications - 149
Citations - 16299
Emilio A. Emini is an academic researcher from Pfizer. The author has contributed to research in topics: Pneumococcal conjugate vaccine & Virus. The author has an hindex of 53, co-authored 149 publications receiving 15634 citations. Previous affiliations of Emilio A. Emini include Stony Brook University & Merck & Co..
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Journal ArticleDOI
Treatment with Indinavir, Zidovudine, and Lamivudine in Adults with Human Immunodeficiency Virus Infection and Prior Antiretroviral Therapy
Roy M. Gulick,John W. Mellors,Diane V. Havlir,Joseph J. Eron,Charles J. Gonzalez,Deborah McMahon,Douglas D. Richman,Fred T. Valentine,Leslie Jonas,Anne R. Meibohm,Emilio A. Emini,Chodakewitz Jeffrey A +11 more
TL;DR: In most HIV-infected patients with prior antiretroviral therapy, the combination of indinavir, zidovudine, and lamivudine reduces levels of HIV RNA to less than 500 copies per milliliter for as long as one year.
Journal ArticleDOI
Active human immunodeficiency virus protease is required for viral infectivity.
Nancy E. Kohl,Emilio A. Emini,William A. Schleif,Lenora Davis,Jill C. Heimbach,Richard A. F. Dixon,Edward M. Scolnick,Irving S. Sigal +7 more
TL;DR: The results demonstrate that the HIV protease is an essential viral enzyme and, consequently, an attractive target for anti-HIV drugs.
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Induction of hepatitis A virus-neutralizing antibody by a virus-specific synthetic peptide.
TL;DR: A structural homology exists between the two viruses, despite minimal primary sequence conservation, and a synthetic peptide containing the HAV-specific amino acid sequence of one of these sites induced anti-HAV-neutralizing antibodies.
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Polysaccharide Conjugate Vaccine against Pneumococcal Pneumonia in Adults
Marc J. M. Bonten,Susanne M. Huijts,Marieke Bolkenbaas,Chris Webber,Scott Patterson,Samantha Gault,Cornelis H. van Werkhoven,Anna M M van Deursen,Elisabeth A. M. Sanders,Theo J M Verheij,Michael Patton,Anne McDonough,Anita Moradoghli-Haftvani,Helen M Smith,Tracey Mellelieu,Michael W. Pride,Graham Crowther,Beate Schmoele-Thoma,Daniel A. Scott,Kathrin U. Jansen,Rita Lobatto,Bas J. Oosterman,Nils Visser,Esther Caspers,Andre J. Smorenburg,Emilio A. Emini,William C. Gruber,Diederick E. Grobbee +27 more
TL;DR: Among older adults, PCV13 was effective in preventing vaccine-type pneumococcal, bacteremic, and noninvasive community-acquired pneumonia and vaccine- type invasive pneumococCal disease but not in preventing community- Acquired pneumonia from any cause.
Journal ArticleDOI
Primary structure, gene organization and polypeptide expression of poliovirus RNA
Naomi Kitamura,Bert L. Semler,Paul G. Rothberg,G R Larsen,Cheryl J. Adler,Andrew J. Dorner,Emilio A. Emini,Ronnie Hanecak,James J. Lee,James J. Lee,Sylvie van der Werf,Sylvie van der Werf,Carl W. Anderson,Eckard Wimmer +13 more
TL;DR: The primary structure of the poliovirus genome has been determined and Twelve viral polypeptides have been mapped by amino acid sequence analysis and were found to be proteolytic cleavage products of the polyprotein, cleavages occurring predominantly at Gln-Gly pairs.