J
James J. Lee
Researcher at Mayo Clinic
Publications - 293
Citations - 32911
James J. Lee is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Eosinophil & Eosinophil peroxidase. The author has an hindex of 79, co-authored 273 publications receiving 28843 citations. Previous affiliations of James J. Lee include California Institute of Technology & Albert Einstein College of Medicine.
Papers
More filters
Journal ArticleDOI
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
TL;DR: It is shown that exosomes contain both mRNA and microRNA, which can be delivered to another cell, and can be functional in this new location, and it is proposed that this RNA is called “exosomal shuttle RNA” (esRNA).
Journal ArticleDOI
Direct observation of the transition from indirect to direct bandgap in atomically thin epitaxial MoSe2
Yi Zhang,Tay-Rong Chang,Bo Zhou,Yong-Tao Cui,Hao Yan,Hao Yan,Zhongkai Liu,Zhongkai Liu,F. Schmitt,F. Schmitt,James J. Lee,James J. Lee,Robert G. Moore,Robert G. Moore,Yulin Chen,Yulin Chen,Yulin Chen,Hsin Lin,Horng-Tay Jeng,Sung-Kwan Mo,Zahid Hussain,Arun Bansil,Zhi-Xun Shen,Zhi-Xun Shen +23 more
TL;DR: The first direct observation of the transition from indirect to direct bandgap in monolayer samples is reported by using angle-resolved photoemission spectroscopy on high-quality thin films of MoSe2 with variable thickness, grown by molecular beam epitaxy.
Journal ArticleDOI
Primary structure, gene organization and polypeptide expression of poliovirus RNA
Naomi Kitamura,Bert L. Semler,Paul G. Rothberg,G R Larsen,Cheryl J. Adler,Andrew J. Dorner,Emilio A. Emini,Ronnie Hanecak,James J. Lee,James J. Lee,Sylvie van der Werf,Sylvie van der Werf,Carl W. Anderson,Eckard Wimmer +13 more
TL;DR: The primary structure of the poliovirus genome has been determined and Twelve viral polypeptides have been mapped by amino acid sequence analysis and were found to be proteolytic cleavage products of the polyprotein, cleavages occurring predominantly at Gln-Gly pairs.
Journal ArticleDOI
Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense
Shida Yousefi,Jeffrey A. Gold,Nicola Andina,James J. Lee,Ann M. Kelly,Evelyne Kozlowski,Inès Schmid,Alex Straumann,Janine Reichenbach,Gerald J. Gleich,Hans-Uwe Simon +10 more
TL;DR: It is shown that lipopolysaccharide from Gram-negative bacteria activates interleukin-5 (IL-5)- or interferon-γ–primed eosinophils to release mitochondrial DNA in a reactive oxygen species–dependent manner, but independent of eosInophil death, suggesting a previously undescribed mechanism of eOSinophil-mediated innate immune responses that might be crucial for maintaining the intestinal barrier function after inflammation-associated epithelial cell damage
Journal ArticleDOI
Defining a link with asthma in mice congenitally deficient in eosinophils.
James J. Lee,Dawn Dimina,Mi Mi P. Macias,Sergei I. Ochkur,Michael P. McGarry,K.R. O'Neill,Cheryl A. Protheroe,R.S. Pero,Thanh H Nguyen,Stephania A. Cormier,Stephania A. Cormier,Elizabeth Lenkiewicz,Dana Colbert,Lisa Rinaldi,Steven J. Ackerman,Charles G. Irvin,Nancy A. Lee +16 more
TL;DR: The development of an eosinophil-less mouse now permits an unambiguous assessment of a number of human diseases that have been linked to this granulocyte, including allergic diseases, parasite infections, and tumorigenesis.