E
Emine Kaya
Researcher at Ludwig Maximilian University of Munich
Publications - 9
Citations - 1528
Emine Kaya is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Amino acid & Click chemistry. The author has an hindex of 8, co-authored 9 publications receiving 1288 citations. Previous affiliations of Emine Kaya include Protein Sciences & University of California, Berkeley.
Papers
More filters
Journal ArticleDOI
Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation
Martin Jinek,Fuguo Jiang,David W. Taylor,David W. Taylor,Samuel H. Sternberg,Emine Kaya,Enbo Ma,Carolin Anders,Michael H. Hauer,Kaihong Zhou,Steven Lin,Matias Kaplan,Anthony T. Iavarone,Emmanuelle Charpentier,Emmanuelle Charpentier,Eva Nogales,Jennifer A. Doudna +16 more
TL;DR: To compare the architectures and domain organization of diverse Cas9 proteins, the atomic structures of Cas9 from Streptococcus pyogenes and Actinomyces naeslundii and AnaCas9 were determined by x-ray crystallography and three-dimensional reconstructions of apo-SpyCas9, SpyCas9:RNA, and SpyCas 9:RNA:DNA were obtained by negative-stain single-particle electron microscopy.
Journal ArticleDOI
A genetically encoded norbornene amino acid for the mild and selective modification of proteins in a copper-free click reaction.
TL;DR: This project shows that requirments for the incorporation of special unnatural amino acid into proteins to enable site-specific bioorthogonal functionalization can be met with a specially encoded norbornene amino acid which reacts selectively with nitrile imines.
Journal ArticleDOI
RNA-dependent RNA targeting by CRISPR-Cas9
TL;DR: It is shown that Cas9 enzymes from both subtypes II-A and II-C can recognize and cleave single-stranded RNA by an RNA-guided mechanism that is independent of a protospacer-adjacent motif (PAM) sequence in the target RNA.
Journal ArticleDOI
The archaeal cofactor F0 is a light-harvesting antenna chromophore in eukaryotes
Andreas F. Glas,Melanie J. Maul,Max J. Cryle,Thomas R. M. Barends,Sabine Schneider,Emine Kaya,Ilme Schlichting,Thomas Carell +7 more
TL;DR: The results show that the F0/F420 coenzyme system, so far believed to be strictly limited to the archael kingdom of life, is far more widespread than anticipated.
Journal ArticleDOI
Synthesis of Threefold Glycosylated Proteins using Click Chemistry and Genetically Encoded Unnatural Amino Acids
TL;DR: In vivo incorporation of up to three artificial alkyne or alkene amino acids into the yellow fluorescent protein (YFP) and the subsequent glycosylation of these sites with different sugar azides using the Huisgen–Meldal–Sharpless click chemistry method, which was used in this group for the synthesis of multiple sugar modified oligonucleotides.