E
Enrique G. Gutierrez
Researcher at Tulane University
Publications - 6
Citations - 1331
Enrique G. Gutierrez is an academic researcher from Tulane University. The author has contributed to research in topics: Blood–brain barrier & Cerebrospinal fluid. The author has an hindex of 5, co-authored 6 publications receiving 1244 citations. Previous affiliations of Enrique G. Gutierrez include Veterans Health Administration.
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Murine tumor necrosis factor alpha is transported from blood to brain in the mouse.
TL;DR: It is shown that murine tumor necrosis factor alpha labeled with 125I (I-mTNF alpha) crosses the blood-brain barrier (BBB) after i.v. injection, suggesting that TNF alpha is sequestered by the brain.
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Penetration of interleukin-6 across the murine blood-brain barrier.
TL;DR: The results suggest that blood-borne IL-6 can reach sites behind the BBB, but that susceptibility to enzymatic degradation may limit contact time within the CNS.
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Blood-borne interleukin-1 receptor antagonist crosses the blood-brain barrier
TL;DR: The results show that IL-1ra circulating in the blood can cross the blood-brain barrier to enter the central nervous system.
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Differential permeability of the BBB in acute EAE: enhanced transport of TNT-alpha
TL;DR: The changes in BBB function during EAE extend beyond disruption to include changes in the saturable transport systems for substances involved in the disease process.
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Interleukin-1α in blood has direct access to cortical brain cells
TL;DR: The results show that circulating IL-1α has direct access to cortical brain cells behind the BBB through a saturable transport system that provides a major pathway by which the brain and immune system interact.