E
Erhard Bremer
Researcher at University of Marburg
Publications - 170
Citations - 12681
Erhard Bremer is an academic researcher from University of Marburg. The author has contributed to research in topics: Bacillus subtilis & Ectoine. The author has an hindex of 61, co-authored 164 publications receiving 11488 citations. Previous affiliations of Erhard Bremer include Max Planck Society & University of Konstanz.
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Journal ArticleDOI
With a pinch of extra salt-Did predatory protists steal genes from their food?
Laura Czech,Erhard Bremer +1 more
TL;DR: Different approaches led to the joint conclusion that these unicellular Eukarya use the salt-out strategy to cope successfully with the persistent high salinity in their habitat.
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Activity of the Osmotically Regulated yqiHIK Promoter from Bacillus subtilis Is Controlled at a Distance
TL;DR: The yqiHIK gene cluster from Bacillus subtilis is predicted to encode an extracellular lipoprotein, a secreted N-acetylmuramoyl-L-alanine amidase, and a cytoplasmic glycerophosphodiester phosphodiesterase, but reverse transcriptase PCR analysis showed that the genes are transcribed as an operon.
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The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine
Alexandra A. Richter,Stefanie Kobus,Laura Czech,Astrid Hoeppner,Jan Zarzycki,Tobias J. Erb,Tobias J. Erb,Lukas Lauterbach,Jeroen S. Dickschat,Erhard Bremer,Sander H. J. Smits +10 more
TL;DR: It is found that (Pl)EctA forms a homodimer whose enzyme activity is highly regiospecific by producing N-γ-ADABA but not the ectoine catabolic intermediate N-α-acetyl-l-2,4-diaminobutyric acid.
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Degradation of the microbial stress protectants and chemical chaperones ectoine and hydroxyectoine by a bacterial hydrolase–deacetylase complex
Christopher-Nils Mais,Lucas Hermann,Florian Altegoer,Andreas Seubert,Alexandra A. Richter,Isa Wernersbach,Laura Czech,Erhard Bremer,Gert Bange +8 more
TL;DR: The combined biochemical and structural results indicate that the EutD homodimer opens the pyrimidine ring of ectoine through an unusual covalent intermediate, N-α-2 acetyl-l-2,4-diaminobutyrate (α-ADABA), which is found to induce the MocR/GabR-type repressor EnuR, which controls the expression of many ectoine catabolic genes clusters.
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Microseeding – A Powerful Tool for Crystallizing Proteins Complexed with Hydrolyzable Substrates
TL;DR: A microseeding protocol is devised leading to crystals of ChoX with bound acetylcholine within 24 hours, with one drawback the high twinning fraction of the crystals, possibly was due to the rapid crystal growth.