Erhard Bremer

TL;DR: Glycine betaine strongly stimulated growth at 15°C and permitted cell proliferation at the growth-inhibiting temperature of 13°C, which highlights an underappreciated facet of the acclimatization of B. subtilis to cold environments and allows a comparison of the characteristics of compatible solutes with respect to their osmotic, heat, and cold stress-protective properties.

TL;DR: It is suggested that environmentally induced changes in DNA supercoiling may play a role in determining the level of porin expression, and these findings have implications for current models of Porin regulation.

TL;DR: The results suggest that the nucleoid-associated DNA-binding protein H-NS (H1a) plays a critical role in gene expression and in determining the structure of the genetic material.

TL;DR: Fluorescence-based ligand binding assays used to quantitate substrate binding by the periplasmic ligand-binding protein ChoX confirmed that ChoX recognizes choline and acetylcholine with high and medium affinity, respectively, and solved the crystal structures of ChoX in a closed, substrate-free conformation.

TL;DR: It is shown that the ability to cope efficiently with a cold environment is strongly impaired in E. coli strains carrying hns mutations, and synthesis of a truncated H-NS protein with only 75 amino-terminal amino acids was insufficient to restore growth at low temperature.