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Eric M. Gordon
Researcher at Princeton University
Publications - 97
Citations - 1271
Eric M. Gordon is an academic researcher from Princeton University. The author has contributed to research in topics: Alkyl & Enkephalinase. The author has an hindex of 19, co-authored 97 publications receiving 1267 citations.
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Journal ArticleDOI
Design of novel inhibitors of aminopeptidases. Synthesis of peptide-derived diamino thiols and sulfur replacement analogues of bestatin.
TL;DR: The design rationale and synthesis of novel peptidyl diamino thiol inhibitors of rat brain aminopeptidase are presented, along with accompanying structure-activity analysis, and speculations on the possible mode of enzyme-inhibitor binding of bestatin are offered.
Journal ArticleDOI
O-Sulfated .beta.-lactam hydroxamic acids (monosulfactams). Novel monocyclic .beta.-lactam antibiotics of synthetic origin
Eric M. Gordon,Miguel A. Ondetti,Jelka Pluscec,Christopher M. Cimarusti,D. P. Bonner,Richard B. Sykes +5 more
Journal ArticleDOI
Phosphinyl acid-based bisubstrate analog inhibitors of ras farnesyl protein transferase
Dinesh V. Patel,Eric M. Gordon,Robert J. Schmidt,Harold N. Weller,M G Young,Robert Zahler,Mariano Barbacid,Joan M. Carboni,Johnni Gullo-Brown,Lisa Hunihan +9 more
TL;DR: A distinctive feature of this novel class of potent and selective bisubstrate FPT inhibitors is that they are non-sulfhydryl in nature.
Journal ArticleDOI
Design of peptide derived amino alcohols as transition-state analog inhibitors of angiotensin converting enzyme.
TL;DR: The resulting modified tripeptides are shown to be a new class of potent inhibitors of converting enzyme.