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Erica L. Huey
Researcher at Harvard University
Publications - 7
Citations - 602
Erica L. Huey is an academic researcher from Harvard University. The author has contributed to research in topics: Thirst & Mechanoreceptor. The author has an hindex of 4, co-authored 7 publications receiving 374 citations. Previous affiliations of Erica L. Huey include University of California, San Francisco & Howard Hughes Medical Institute.
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Journal ArticleDOI
Genetic Identification of Vagal Sensory Neurons That Control Feeding.
Ling Bai,Sheyda Mesgarzadeh,Karthik S. Ramesh,Erica L. Huey,Yin Liu,Lindsay A. Gray,Tara J. Aitken,Yiming Chen,Lisa R. Beutler,Jamie S. Ahn,Linda Madisen,Hongkui Zeng,Mark A. Krasnow,Zachary A. Knight +13 more
TL;DR: It is found that food intake is most sensitive to stimulation of mechanoreceptors in the intestine, whereas nutrient-activated mucosal afferents have no effect, and a key role is identified in the regulation of feeding.
Journal ArticleDOI
Thirst neurons anticipate the homeostatic consequences of eating and drinking
Christopher A. Zimmerman,Yen-Chu Lin,David E. Leib,Ling Guo,Erica L. Huey,Gwendolyn E. Daly,Yiming Chen,Zachary A. Knight +7 more
TL;DR: An unexpected role for the subfornical organ (SFO) in the anticipatory regulation of thirst in mice is revealed and a neural mechanism to explain longstanding behavioural observations, including the prevalence of drinking during meals, the rapid satiation of thirst, and the fact that oral cooling is thirst-quenching.
Journal ArticleDOI
A gut-to-brain signal of fluid osmolarity controls thirst satiation
Christopher A. Zimmerman,Erica L. Huey,Erica L. Huey,Jamie S. Ahn,Jamie S. Ahn,Lisa R. Beutler,Chan Lek Tan,Chan Lek Tan,Seher Kosar,Ling Bai,Yiming Chen,Timothy V. Corpuz,Linda Madisen,Hongkui Zeng,Zachary A. Knight +14 more
TL;DR: It is demonstrated that individual neurons compute homeostatic need by integrating this gastrointestinal osmosensory information with oropharyngeal and blood-borne signals and how the fluid homeostasis system monitors the osmolarity of ingested fluids to dynamically control drinking behaviour.
Journal ArticleDOI
The Forebrain Thirst Circuit Drives Drinking through Negative Reinforcement.
David E. Leib,Christopher A. Zimmerman,Ailar Poormoghaddam,Erica L. Huey,Jamie S. Ahn,Yen-Chu Lin,Chan Lek Tan,Yiming Chen,Zachary A. Knight +8 more
TL;DR: The motivational mechanism by which the forebrain thirst circuit drives drinking is described, showing that thirst-promoting subfornical organ neurons are negatively reinforcing and that this negative-valence signal is transmitted along projections to the organum vasculosum of the lamina terminalis and median preoptic nucleus.
Journal ArticleDOI
Mechanoreceptor synapses in the brainstem shape the central representation of touch
Brendan P. Lehnert,Celine Santiago,Celine Santiago,Erica L. Huey,Erica L. Huey,Alan J. Emanuel,Alan J. Emanuel,Sophia Renauld,Sophia Renauld,Nusrat Africawala,Nusrat Africawala,Ilayda Alkislar,Ilayda Alkislar,Yang Zheng,Yang Zheng,Ling Bai,Ling Bai,Charalampia Koutsioumpa,Charalampia Koutsioumpa,Jennifer T. Hong,Jennifer T. Hong,Alexandra R. Magee,Alexandra R. Magee,Christopher D. Harvey,David D. Ginty,David D. Ginty +25 more
TL;DR: This article found that the skin region a mechanoreceptor innervates controls the developmental refinement of its central synapses to shape the representation of touch in the brain, such that those innervating glabrous skin make synaptic connections that expand their central representation.