Ericka Peterson

TL;DR: In pathological gamblers dopamine release in the ventral striatum appears to be associated with increased excitement levels despite lower IGT performance, which might suggest a 'double deficit' function of dopamine in pathological gambling.

TL;DR: Dopamine release in ventral striatum of pathological gamblers losing money is found to be higher in those with a gambling history than in those without a history of gambling.

TL;DR: Investigation of dopamine release in the ventral striatum in relation to gambling performance on the Iowa Gambling Task showed that Pathological Gamblers with dopamine release had significantly lower IGT performance than Healthy Controls, and dopamine release was associated with significantly higher I GT performance in Healthy Controls and significantly lowerIGT performance in PathologicalGamblers.

TL;DR: The data supported an inverse U-shaped relation between striatal dopamine release and IGT performance if the pathological gambling group, but not in the healthy control group, and suggest that dopaminergic sensitivity to uncertainty is pronounced in pathological gambling, butNot among non-gambling healthy controls.

TL;DR: It is concluded that SCR is less conditioned by dopaminergic activity in highly sensation-seeking subjects, regardless of PG status.