E
Erik Lindahl
Researcher at Science for Life Laboratory
Publications - 192
Citations - 69645
Erik Lindahl is an academic researcher from Science for Life Laboratory. The author has contributed to research in topics: Ligand-gated ion channel & Ion channel. The author has an hindex of 55, co-authored 174 publications receiving 54950 citations. Previous affiliations of Erik Lindahl include Stanford University & Swiss Institute of Bioinformatics.
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Copernicus, a hybrid dataflow and peer-to-peer scientific computing platform for efficient large-scale ensemble sampling
TL;DR: This work presents how these challenges are addressed with combinations of dataflow programming, peer-to-peer techniques and peer- to-peer networks in the Copernicus platform, which allows automation of sampling-focused workflows, task generation, dependency tracking, and not least distributing these to a diverse set of compute resources.
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Determining the molecular basis of voltage sensitivity in membrane proteins.
TL;DR: A computational approach to predict voltage-sensing elements in any membrane protein, independent of its structure or function, is provided and enables a characterization of voltage sensitivity that goes beyond mere identification of charges.
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Solvent diffusion outside macromolecular surfaces
Erik Lindahl,Olle Edholm +1 more
TL;DR: In this paper, the effect of inhomogeneous environment upon solvent molecules close to a macromolecular surface is evaluated from a molecular-dynamics simulation of a protein, myoglobin, in water solution.
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Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel
TL;DR: Structural, functional, and normal-mode analysis of two conformational states of a multidomain pLGIC, called DeCLIC, from a Desulfofustis deltaproteobacterium are reported, including a periplasmic NTD fused to the conventional ligand-binding domain (LBD).